Evidence map›Paper›PMID 27825605›Full record

ReviewBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2016

Antimicrobial resistance in Enterobacteriaceae in Brazil: focus on β-lactams and polymyxins.

Jorge Luiz Mello Sampaio, Ana Cristina Gales

Open access · hybridAbstract readReview
In one paragraph

Review in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Guideline for antimicrobial treatment of multidrug-resistant Gram-negative infections: practice recommendations of the Brazilian Society of Infectious Diseases.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Guideline
  2. Article
  3. Article
  4. Article
  5. Epidemiological and molecular study of Providencia rettgeri outbreak at a university hospital during the COVID-19 reference center.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  6. Review
  7. Article
  8. Emergence of multidrug-resistantOne health (Amsterdam, Netherlands) · 2024
    Article
  9. Polymyxin resistance in Enterobacter cloacae complex in Brazil: phenotypic and molecular characterization.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  10. Article
  11. First Detection of International High-RiskTransboundary and emerging diseases · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. One health clones of multidrug-resistantOne health (Amsterdam, Netherlands) · 2023
    Article
  17. Characterization ofAntibiotics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Genomic Diversity of NDM-ProducingAntibiotics (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jorge Luiz Mello SampaioUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas, Departamento de Análises Clínicas e Toxicológicas, São Paulo, SP, Brazil; Fleury Medicina e Saúde, Seção de Microbiologia, São Paulo, SP, Brazil. Electronic address: sampaio@usp.br.
Ana Cristina GalesUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina Interna, São Paulo, Brazil. Electronic address: ana.gales@gmail.com.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last 30 years there has been a dissemination of plasmid-mediated β-lactamases in Enterobacteriaceae in Brazil. Extended spectrum β-lactamases (ESBL) are widely disseminated in the hospital setting and are detected in a lower frequency in the community setting. Cefotaximases are the most frequently detected ESBL type and Klebsiella pneumoniae is the predominant species among ESBL producers. Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae became widely disseminated in Brazil during the last decade and KPC production is currently the most frequent resistance mechanism (96.2%) in carbapenem resistant K. pneumoniae. To date KPC-2 is the only variant reported in Brazil. Polymyxin B resistance in KPC-2-producing K. pneumoniae has come to an alarming rate of 27.1% in 2015 in São Paulo, the largest city in Brazil. New Delhi metallo-β-lactamase was detected in Brazil in 2013, has been reported in different Brazilian states but are not widely disseminated. Antimicrobial resistance in Enterobacteriaceae in Brazil is a very serious problem that needs urgent actions which includes both more strict adherence to infection control measures and more judicious use of antimicrobials.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsAnti-Infective AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamsBrazilEnterobacteriaceaeEnterobacteriaceae InfectionsHumansPlasmidsPolymyxinsAmpC beta-lactamasesAnti-Bacterial AgentsAnti-Infective AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamscarbapenemasePolymyxinsAntimicrobial resistanceBrazilCarbapenemasesColistinEnterobacteriaceaeESBLExtended spectrum β-lactamasesKlebsiella pneumoniae carbapenemaseKPCNDMNew Delhi metallo-β-lactamasePolymyxin B

Identifiers

PMID27825605
PMCPMC5156504
OpenAlexW2538077101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.