ArticleBMC infectious diseases2016
Human tuberculosis caused by Mycobacterium bovis: a retrospective comparison with Mycobacterium tuberculosis in a Mexican tertiary care centre, 2000-2015.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Continental Prevalence of Tuberculosis Infection and Associated Risk Factors From African Cattle: Systematic Review and Meta-Analysis.Veterinary medicine and science · 2026Pooled it
- Zoonotic Tuberculosis and Dairy Products: Comprehensive Meta-Analysis of Prevalence and Public Health Implications.Veterinary medicine and science · 2025Pooled it
- Global prevalence of Mycobacterium bovis infections among human tuberculosis cases: Systematic review and meta-analysis.Zoonoses and public health · 2021Pooled it
- Trial
- Clinical Characteristics of People With Extrapulmonary and Disseminated Tuberculosis: A 23-Year Retrospective Cohort Study in People Without HIV Without Pharmacological Immunosuppression.Open forum infectious diseases · 2026Article
- Epidemiology of extrapulmonary tuberculosis, Alameda County, California, 2010-2021.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- A Droplet Digital PCR Method for Simultaneous Detection and Quantification ofFoods (Basel, Switzerland) · 2026Article
- Molecular Insights into Anabaenopeptin-Mediated Inhibition of Protein Tyrosine Phosphatase B in theACS omega · 2026Article
- Modified protein selection strategy based on Escherichia coli's Hitchhiker transport and validation through selection of nanobodies targeting bovine interferon gamma.Scientific reports · 2026Article
- Tuberculosis in advanced chronic kidney disease: An Observational Study at a Tertiary Care Center in Mexico.PloS one · 2026Observational
- Exploring transmission dynamics in epidemiologically linked pulmonary tuberculosis cases and household contacts: a WGS-based investigation.BMC genomics · 2025Article
- Article
- Syphilis and HIV co-infection presenting with a pituitary abscess: A rare case presentation.Radiology case reports · 2025Article
- High Mycobacterium bovis Exposure but Low IGRA Positivity in UK Farm Workers.Zoonoses and public health · 2025Article
- Distinct Clinical Features of Extrapulmonary and Disseminated Tuberculosis in HIV- and Non-HIV-Associated Immunosuppression: A Retrospective Cohort Study.Open forum infectious diseases · 2025Article
- Phylogenetic analysis of Mycobacterium bovis reveals animal and zoonotic tuberculosis spread between Morocco and European countries.PLoS neglected tropical diseases · 2025Article
- Article
- Polyfunctionality of CD4Frontiers in immunology · 2025Article
- Genetic diversity and antibiotic resistance ofFrontiers in cellular and infection microbiology · 2025Article
- Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman tuberculosis caused by Mycobacterium bovis is believed to be frequent in developing countries. Transmission is usually through ingestion of unpasteurized dairy products, although airborne contagion is possible. Disease caused by M. tuberculosis or M. bovis is clinically indistinguishable from each other. The aim of this study was to determine the factors associated with M. bovis disease.
methodsRetrospective analysis of all culture-positive cases of M. bovis and M. tuberculosis from 2000 to 2015, in a Mexican tertiary-care centre. Sociodemographic, clinical, and radiographic data from medical records were compared. Disease site was classified as pulmonary, extrapulmonary, or pulmonary and extrapulmonary, based on cultures.
resultsWe evaluated 533 cases, 372 (69.7 %) of which were caused by M. tuberculosis and 161 (30.2 %) by M. bovis. Characteristics associated with M. bovis disease were: younger age (aOR 0.97, 95 % CI 0.95-0.98), glucocorticoid use (aOR 2.27, 95 % CI 1.42-3.63), and extrapulmonary disease (aOR 1.80, 95 % CI 1.21-2.69). M. tuberculosis was associated with lower socioeconomic status (aOR 0.52, 95 % CI 0.28-0.97). When we analysed only pulmonary cases, younger age (aOR 0.97, 95 % CI 0.96-0.99), glucocorticoid use (aOR 2.41, 95 % CI 1.30-4.46), and smoking (aOR 1.94, CI 95 % 1.15-3.27) were associated with M. bovis. Both groups showed similar proportions of direct microscopy smear results (respiratory samples) and chest X-ray cavitations.
conclusionsYounger age, glucocorticoid use, and extrapulmonary disease were associated with M. bovis as the causative agent of tuberculosis in a group of patients from a tertiary care centre in a country where bovine tuberculosis is endemic. Further studies must be conducted in the general population to determine pathogen-specific associated factors and outcomes.
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