SynthesisPloS one2016
Meta-Analysis of the Association between Tea Intake and the Risk of Cognitive Disorders.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Tea intake or consumption and the risk of dementia: a meta-analysis of prospective cohort studies.PeerJ · 2023Pooled it
- Association Between Tea Drinking and Cognitive Disorders in Older Adults: A Meta-Analysis of Observational Studies.Frontiers in aging neuroscience · 2022Pooled it
- Pooled it
- Clinical insights into catechin-based nanomedicine: a review of therapeutic potential in neurodegenerative diseases.3 Biotech · 2025Review
- Green Tea Mitigates the Hallmarks of Aging and Age-Related Multisystem Deterioration.Aging and disease · 2025Review
- Moderate tea consumption and dementia-related neuroimaging markers.Frontiers in neurology · 2025Article
- Association of lifestyle, dietary pattern, and liver function with cognition in older adults: findings from a cross-sectional study.Frontiers in nutrition · 2025Article
- Maintaining long-term frequent tea consumption could reduce the risk of cognitive decline: results from a 10-year longitudinal study.Frontiers in nutrition · 2025Article
- Isolation and antioxidant characterization of theaflavin for neuroprotective effect in mice model.Food science & nutrition · 2023Article
- Acute effects of (-)-gallocatechin gallate-rich green tea extract on the cerebral hemodynamic response of the prefrontal cortex in healthy humans.Frontiers in neuroergonomics · 2023Article
- Catechins as a Potential Dietary Supplementation in Prevention of Comorbidities Linked with Down Syndrome.Nutrients · 2022Review
- Association of Alcohol Types, Coffee, and Tea Intake with Risk of Dementia: Prospective Cohort Study of UK Biobank Participants.Brain sciences · 2022Article
- Review
- Effect of Polyphenols on Cognitive Function: Evidence from Population-Based Studies and Clinical Trials.The journal of nutrition, health & aging · 2021Review
- The Neuroprotective Effects of Moderate and Regular Caffeine Consumption in Alzheimer's Disease.Oxidative medicine and cellular longevity · 2021Review
- Caffeinated Coffee and Tea Consumption, Genetic Variation and Cognitive Function in the UK Biobank.The Journal of nutrition · 2020Article
- Regardless of the Brewing Conditions, Various Types of Tea are a Source of Acetylcholinesterase Inhibitors.Nutrients · 2020Article
- Plant-Based Dietary Patterns, Plant Foods, and Age-Related Cognitive Decline.Advances in nutrition (Bethesda, Md.) · 2019Review
- Making DEEP Sense of Lifestyle Risk and Resilience.Frontiers in aging neuroscience · 2019Article
- Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease.Neurochemical research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlzheimer's disease is a common neurodegenerative disorder in elderly. This study was aimed to systematically evaluate the association between tea intake and the risk of cognitive disorders by meta-analysis. METHODS AND
findingsPubMed, Embase and Wanfang databases were systematically searched and a total of 26 observational studies were included in this study. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) were calculated and pooled by using fixed or random effects models according to the degree of heterogeneity.
resultsThe overall pooled analysis indicated that tea intake could significantly reduce the risk of cognitive disorders (OR = 0.65, 95%CI = 0.58-0.73). Subgroup analyses were conducted based on study design, population, frequency of tea drinking and type of cognitive disorders. The results showed that tea drinking was significantly associated with the reduced incidence of cognitive disorders in all of subgroups based on study design and frequency of tea drinking. In particular, tea drinking was inversely associated with the risk of cognitive impairment (CoI), mild cognitive impairment (MCI), cognitive decline and ungrouped cognitive disorders. Moreover, for population subgroups, the significant association was only found in Chinese people.
conclusionOur study suggests that daily tea drinking is associated with decreased risk of CoI, MCI and cognitive decline in the elderly. However, the association between tea intake and Alzheimer's disease remains elusive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.