ArticleAJR. American journal of roentgenology2017
The Value of Secretin-Enhanced MRCP in Patients With Recurrent Acute Pancreatitis.
Article in AJR. American journal of roentgenology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- AEG-AESPANC-OPGE-SIED-SPG Ibero-Latin American Guidelines on Acute Pancreatitis (iLATAM-AP).United European gastroenterology journal · 2026Guideline
- Evidence-based clinical practice guidelines for chronic pancreatitis 2021.Journal of gastroenterology · 2022Review
- Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: The Role of Oxidative Stress-Induced DNA Damage Signaling.Biomedicines · 2022Article
- The role of imaging in acute pancreatitis.La Radiologia medica · 2021Article
- Wirsungocele: evaluation by MRCP and clinical significance.Abdominal radiology (New York) · 2021Article
- Advanced MR Imaging of the Pancreas.Magnetic resonance imaging clinics of North America · 2020Review
- Biliary anatomy and pancreatic duct variations: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2020Article
- Functional Pancreatic Sphincter Dysfunction in Children: Recommendations for Diagnosis and Management.Journal of pediatric gastroenterology and nutrition · 2019Review
- Identification and management of pancreas divisum.Expert review of gastroenterology & hepatology · 2019Review
- Recent advances in the diagnosis and management of chronic pancreatitis.The Korean journal of internal medicine · 2019Review
- The clinical value of secretin-enhanced MRCP in the functional and morphological assessment of pancreatic diseases.The British journal of radiology · 2018Review
- Article
- Nationwide epidemiological survey of early chronic pancreatitis in Japan.Journal of gastroenterology · 2017Article
- The future of ERCP.Endoscopy international open · 2017Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this study is to assess the additional value of secretin-enhanced MRCP over conventional (non-secretin-enhanced) MRCP in diagnosing disease in patients with recurrent acute pancreatitis. MATERIALS AND
methodsA retrospective review of a radiology database found 72 patients with recurrent acute pancreatitis who had secretin-enhanced MRCP and ERCP correlation within 3 months of each other between January 2007 and December 2011. Of these patients, 54 had no history of pancreatic tumor or surgery and underwent MRI more than 3 months after an episode of acute pancreatitis. In addition, 57 age- and sex-matched control subjects with secretin-enhanced MRCP and ERCP correlation and without a diagnosis of recurrent acute pancreatitis or chronic pancreatitis were enrolled as the control group. All studies were anonymized, and secretin-enhanced MRCP images (image set A) were separated from conventional 2D and 3D MRCP and T2-weighted images (image set B). Image sets A and B for each patient were assigned different and randomized case numbers. Two blinded reviewers independently assessed both image sets for ductal abnormalities and group A image sets for exocrine response to secretin.
resultsThere were statistically significantly more patients with recurrent acute pancreatitis with reduced exocrine function compared with patients in the control group (32% vs 9%; p < 0.01) on secretin-enhanced images. Patients with recurrent acute pancreatitis were more likely to have side branch dilation (p = 0.02; odds ratio, 3.6), but not divisum, compared with the control group. Secretin-enhanced images were superior to non-secretin-enhanced images for detecting ductal abnormalities in patients with recurrent acute pancreatitis, with higher sensitivity (76% vs 56%; p = 0.01) and AUC values (0.983 vs 0.760; p < 0.01).
conclusionUp to one-third of patients with recurrent acute pancreatitis showed exocrine functional abnormalities. Secretin-enhanced MRCP had a significantly higher yield for ductal abnormalities than did conventional MRI and should be part of the MRCP protocol for investigation of patients with recurrent acute pancreatitis.
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