ArticleScientific reports2016
Conspecific injury raises an alarm in medaka.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 24 citations in OpenAlex.
- Correlated evolution of core skin structures in freshwater fishes and challenges to epidermal club cells as the material basis of alarm responses.Frontiers in zoology · 2026Article
- Social context prevents heat hormetic effects against mutagens during fish development.FEBS letters · 2025Article
- Putative chemical cue fromParasitology · 2023Article
- Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics.International journal of molecular sciences · 2021Article
- Computational geometric tools for quantitative comparison of locomotory behavior.Scientific reports · 2019Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the late 1930s, Karl von Frisch reported that semiochemicals released upon injury, act as alarm substances (Schreckstoff) in fish. In Ostariophysi species, club cells in the epidermis are believed to contain cues related to alarm substance; however, the function of club cells, primarily as reservoirs of alarm substance has been debated. Here, I describe an alarm response in the Japanese rice fish Oryzias latipes (medaka), a member of the order Beloniformes. The response to alarm substance (Schreckreaction) in medaka is characterized by bouts of immobility and an increase in cortisol levels within minutes of exposure to conspecific skin extract. Histological analysis, however, suggests that club cells are either rare or absent in the medaka epidermis. In addition to describing an uncharacterized behavior in a vertebrate popular for genetic and developmental studies, these results support the hypothesis that the primary function of epidermal club cells may be unrelated to a role as alarm substance cells. The existence of similar behavioral responses in two evolutionarily distant but well established laboratory models, the zebrafish and the medaka, offers the possibility of comparative analyses of neural circuits encoding innate fear.
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