ArticleScientific reports2016
Photoswitchable non-fluorescent thermochromic dye-nanoparticle hybrid probes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed.
- Carbon Quantum Dots as a Luminescent Platform for Photoswitchable Bioactive Hybrids: Tuning Butyrylcholinesterase Inhibition Through Functional Group Engineering.Nanomaterials (Basel, Switzerland) · 2026Article
- Stimuli-responsive smart materials enabled high-performance biosensors for liquid biopsies.Journal of nanobiotechnology · 2025Review
- Multiscale photoacoustic tomography using reversibly switchable thermochromics.Journal of biomedical optics · 2023Article
- Assembling Near-Infrared Dye on the Surface of Near-Infrared Silica-Coated Copper Sulphide Plasmonic Nanoparticles.Nanomaterials (Basel, Switzerland) · 2023Article
- Application of Nanomaterials in Biomedical Imaging and Cancer Therapy.Nanomaterials (Basel, Switzerland) · 2020Review
- Excellent Temperature-Control Based on Reversible Thermochromic Materials for Light-Driven Phase Change Materials System.Molecules (Basel, Switzerland) · 2019Article
- Photoacoustic temperature imaging based on multi-wavelength excitation.Photoacoustics · 2019Article
- Thermo-Sensitive Nanomaterials: Recent Advance in Synthesis and Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Photoswitchable fluorescent proteins with controllable light-dark states and spectral shifts in emission in response to light have led to breakthroughs in the study of cell biology. Nevertheless, conventional photoswitching is not applicable for weakly fluorescent proteins and requires UV light with low depth penetration in bio-tissue. Here we introduce a novel concept of photoswitchable hybrid probes consisting of thermochromic dye and absorbing nanoparticles, in which temperature-sensitive light-dark states and spectral shifts in absorption can be switched through controllable photothermal heating of doped nanoparticles. The proof-of-concept is demonstrated through the use of two different types of temperature-sensitive dyes doped with magnetic nanoparticles and reversibly photoswitched by a near-infrared laser. Photoacoustic imaging revealed the high contrast of these probes, which is sufficient for their visualization in cells and deep tissue. Our results suggest that these new photoswitchable multicolour probes can be used for multimodal cellular diagnostics and potentially for magnetic and photothermal therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.