ArticleChinese medical journal2016
Analysis of In-hospital Neonatal Death in the Tertiary Neonatal Intensive Care Unit in China: A Multicenter Retrospective Study.
Article in Chinese medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Enhancing perinatal care in Rwanda: building quality improvement into system strengthening.BMJ paediatrics open · 2026Review
- Predictors of neonatal mortality among neonates in Tigray regional state, Ethiopia: A cross-sectional study.PloS one · 2024Article
- Care practices and short-term clinical outcomes of very low birth weight infants in Yangtze River Delta in China.BMC pediatrics · 2022Article
- Infant mode of death in the neonatal intensive care unit: A systematic scoping review.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Estimated Survival and Major Comorbidities of Very Preterm Infants Discharged Against Medical Advice vs Treated With Intensive Care in China.JAMA network open · 2021Article
- Clinical risk factors for the development of late-onset circulatory collapse in premature infants.Pediatric research · 2021Article
- Outcome of very preterm infants delivered outside tertiary perinatal centers in China: a multi-center cohort study.Translational pediatrics · 2021Article
- Associations Between Trajectory of Different Blood Pressure Components in Pregnancy and Risk of Adverse Birth Outcomes - A Real World Study.Risk management and healthcare policy · 2021Article
- Incidence and predictors of neonatal mortality among neonates admitted in Amhara regional state referral hospitals, Ethiopia: prospective follow up study.BMC pediatrics · 2020Article
- Mortality and Morbidity in Infants <34 Weeks' Gestation in 25 NICUs in China: A Prospective Cohort Study.Frontiers in pediatrics · 2020Article
- Correlation between serum transforming growth factor β1, interleukin-6 and neonatal respiratory distress syndrome.Experimental and therapeutic medicine · 2019Article
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Authors and funding
29 authors at 20 institutions in 1 country.
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Abstract
backgroundGlobally, the proportion of child deaths that occur in the neonatal period remains a high level of 37-41%. Differences of cause in neonate death exist in different regions as well as in different economic development countries. The specific aim of this study was to investigate the causes, characteristics, and differences of death in neonates during hospitalization in the tertiary Neonatal Intensive Care Unit (NICU) of China.
methodsAll the dead neonates admitted to 26 NICUs were included between January l, 2011, and December 31, 2011. All the data were collected retrospectively from clinical records by a designed questionnaire. Data collected from each NICU were delivered to the leading institution where the results were analyzed.
resultsA total of 744 newborns died during the 1-year survey, accounting for 1.2% of all the neonates admitted to 26 NICUs and 37.6% of all the deaths in children under 5 years of age in these hospitals. Preterm neonate death accounted for 59.3% of all the death. The leading causes of death in preterm and term infants were pulmonary disease and infection, respectively. In early neonate period, pulmonary diseases (56.5%) occupied the largest proportion of preterm deaths while infection (27%) and neurologic diseases (22%) were the two main causes of term deaths. In late neonate period, infection was the leading cause of both preterm and term neonate deaths. About two-thirds of neonate death occurred after medical care withdrawal. Of the cases who might survive if receiving continuing treatment, parents' concern about the long-term outcomes was the main reason of medical care withdrawal.
conclusionsNeonate death still accounts for a high proportion of all the deaths in children under 5 years of age. Our study showed the majority of neonate death occurred in preterm infants. Cause of death varied with the age of death and gestational age. Accurate and prompt evaluation of the long-term outcomes should be carried out to guide the critical decision.
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