SynthesisOncotarget2016
Efficacy of splint therapy for the management of temporomandibular disorders: a meta-analysis.
Synthesis in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Occlusal Splint Therapy in the Management of Temporomandibular Disorders-Evidence from Systematic Reviews.Journal of oral rehabilitation · 2026Pooled it
- The efficacy of anterior repositioning splints in the management of temporomandibular disc displacement: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study.Medicina (Kaunas, Lithuania) · 2020Trial
- Comparative evaluation of occlusal splint therapy and muscle energy technique in the management of temporomandibular disorders: A randomized controlled clinical trial.Journal of Indian Prosthodontic SocietyTrial
- A novel posterior occlusal splint improves symptoms and prognosis of coexisting temporomandibular disorders and deep bite: a retrospective study.Clinical oral investigations · 2026Article
- Pilot clinical comparison of three occlusal splint fabrication techniques: A preliminary study.Scientific reports · 2025Article
- Painful yawning and temporomandibular disorder: a cross-sectional study among Italian patients.BMC oral health · 2025Article
- A Thermal Imaging Camera as a Diagnostic Tool to Study the Effects of Occlusal Splints on the Elimination of Masticatory Muscle Tension.Dentistry journal · 2025Article
- Comparative Effectiveness of Digitally and Conventionally Fabricated Occlusal Splints with Low-Power Laser Therapy in Treating Temporomandibular Disorders.Journal of lasers in medical sciences · 2025Article
- Umbilical and Placental Derivatives in Temporomandibular Joint Treatment: A Systematic Review.Journal of clinical medicine · 2024Review
- Manual Therapy Techniques Versus Occlusal Splint Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis.Dentistry journal · 2024Review
- Temporomandibular joint space variation and masticatory muscle activation during clenching with full versus partial covering occlusal splints.Clinical oral investigations · 2024Article
- Impact of manual therapy on body posture-3-D analysis with rasterstereography - pilotstudy.Head & face medicine · 2024Article
- Efficacy of acupuncture on craniomandibular myofascial pain in temporomandibular disorder patients: A systematic review.Heliyon · 2024Article
- Effectiveness and safety of hominis placental pharmacopuncture for chronic temporomandibular disorder: A multi-center randomized controlled trial.Integrative medicine research · 2024Article
- Article
- Chronic temporomandibular disorder pain patients with a history of neuropathic pain treatment: a narrative research on their diagnosis and treatment history.BMC oral health · 2024Article
- Effects of storage and toothbrush simulation on Martens hardness of CAD/CAM, hand-cast, thermoforming, and 3D-printed splint materials.Clinical oral investigations · 2023Article
- Efficacy of the transcutaneous electrostimulation in treatment dysfunctions of the TMJ associated with occlusion distortions.BMC oral health · 2023Article
- Temporomandibular treatments are significantly efficient in improving otologic symptoms.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temporomandibular disorders (TMD) are a group of clinical problems affecting temporomandibular joint (TMJ), myofascial muscles and other related structures. Splint therapy is the most commonly used approach to treatment of TMD, but its effectiveness is remains unclear. We therefore conducted a meta-analysis to evaluate the effectiveness of splint therapy for TMD in adults. The electronic databases PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov were searched for reports published up to March 31, 2016. Thirteen eligible studies involving 538 patients were identified. The results indicated that splint therapy increased maximal mouth opening (MMO) for patients with a MMO <45mm and reduced pain intensity measured using the visual analogue scale (VAS) for patients with TMD without specific description (TMDSD). Splint therapy also reduced the frequency of painful episodes for patients with TMJ clicking. No publication bias was observed, as determined with Egger's test for all outcomes. On the basis of this evidence, we recommend the use of splints for the treatment and control of TMD in adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.