ArticleThe Journal of pediatrics2017
Weight Gain and Height Growth during Infancy, Childhood, and Adolescence as Predictors of Adult Cardiovascular Risk.
Article in The Journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Maternal Vitamin B12 Status During Pregnancy and Its Association With Outcomes of Pregnancy and Health of the Offspring: A Systematic Review and Implications for Policy in India.Frontiers in endocrinology · 2021Pooled it
- Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Life-course trajectories of cardiovascular disease risk factors in rural India: Andhra Pradesh Children and Parents Study (APCAPS) 2003-2023.International journal of epidemiology · 2026Article
- Unraveling the genetic links between stature and disease in East Asians: A multi-biobank genetic correlation and risk prediction study.PLoS genetics · 2026Article
- Association of childhood-to-adolescence body mass index trajectories with elevated blood pressure and elevated carotid intima-media thickness.Frontiers in nutrition · 2025Article
- Longitudinal Analysis of Latvian Child Growth: Anthropometric Parameters Dynamics from Birth to Adolescence.Children (Basel, Switzerland) · 2024Article
- Development of a Fitness Surveillance System to Track and Evaluate Obesity in North Idaho.The Journal of school health · 2024Article
- Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.Genome biology · 2024Article
- The burgeoning cardiovascular disease epidemic in Indians - perspectives on contextual factors and potential solutions.The Lancet regional health. Southeast Asia · 2023Review
- Birth conditions nutritional status in childhood associated with cardiometabolic risk factors at 30 years of age: a cohort study.Cadernos de saude publica · 2023Article
- Linear growth and relative weight gain in childhood and bone mass in adolescence: findings from the Pelotas (Brazil) 2004 birth cohort.Archives of osteoporosis · 2022Article
- Patterns of Early Life Weight Gain and Female Onset of Puberty.Journal of the Endocrine Society · 2021Article
- Dynamic alterations in linear growth and endocrine parameters in children with obesity and height reference values.EClinicalMedicine · 2021Article
- Food insecurity, dietary acid load, dietary energy density and anthropometric indices among Iranian children.Eating and weight disorders : EWD · 2021Article
- Changes in Body Size during Early Growth Are Independently Associated with Arterial Properties in Early Childhood.Journal of cardiovascular development and disease · 2021Article
- Childhood socio-economic conditions and risk of cardiovascular disease: results from a pooled sample of 14 011 adults from India.Journal of epidemiology and community health · 2020Article
- Early Programming of Adult Systemic Essential Hypertension.International journal of molecular sciences · 2020Review
- Adjustment for time-invariant and time-varying confounders in 'unexplained residuals' models for longitudinal data within a causal framework and associated challenges.Statistical methods in medical research · 2019Article
- Infant Growth and Long-term Cardiometabolic Health: a Review of Recent Findings.Current nutrition reports · 2019Review
- Associations of growth from birth to puberty with blood pressure and lipid profile at ~17.5 years: evidence from Hong Kong's "Children of 1997" birth cohort.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesTo investigate independent relationships of childhood linear growth (height gain) and relative weight gain to adult cardiovascular disease (CVD) risk traits in Asian Indians. STUDY
designData from 2218 adults from the Vellore Birth Cohort were examined for associations of cross-sectional height and body mass index (BMI) and longitudinal growth (independent conditional measures of height and weight gain) in infancy, childhood, adolescence, and adulthood with adult waist circumference (WC), blood pressure (BP), insulin resistance (homeostatic model assessment-insulin resistance [HOMA-IR]), and plasma glucose and lipid concentrations.
resultsHigher BMI/greater conditional relative weight gain at all ages was associated with higher adult WC, after 3 months with higher adult BP, HOMA-IR, and lipids, and after 15 years with higher glucose concentrations. Taller adult height was associated with higher WC (men β = 2.32 cm per SD, women β = 1.63, both P < .001), BP (men β = 2.10 mm Hg per SD, women β = 1.21, both P ≤ .001), and HOMA-IR (men β = 0.08 log units per SD, women β = 0.12, both P ≤ .05) but lower glucose concentrations (women β = -0.03 log mmol/L per SD P = .003). Greater height or height gain at all earlier ages were associated with higher adult CVD risk traits. These positive associations were attenuated when adjusted for adult BMI and height. Shorter length and lower BMI at birth were associated with higher glucose concentration in women.
conclusionsGreater height or weight gain relative to height during childhood or adolescence was associated with a more adverse adult CVD risk marker profile, and this was mostly attributable to larger adult size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.