Evidence map›Paper›PMID 27822926›Full record

ArticleJournal of Korean medical science2016

Effectiveness of Varicella Vaccination Program in Preventing Laboratory-Confirmed Cases in Children in Seoul, Korea.

Young Hwa Lee, Young June Choe, Sung Il Cho, Cho Ryok Kang, Ji Hwan Bang, Myoung Don Oh, Jong Koo Lee

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Global varicella vaccination programs.Clinical and experimental pediatrics · 2022
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  20. Global impact of varicella vaccination programs.Human vaccines & immunotherapeutics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Young Hwa LeeSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0003-2073-993X
Young June ChoeSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0003-2733-0715
Sung Il ChoSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0003-4085-1494
Cho Ryok KangSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0002-9212-8292
Ji Hwan BangSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0002-7628-1182
Myoung Don OhSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0002-2344-7695
Jong Koo LeeSeoul Center for Infectious Disease Control, Seoul, Korea.ORCID http://orcid.org/0000-0003-4833-1178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A universal one-dose varicella vaccination program was introduced in 2005 in Republic of Korea. However, the incidence of varicella in Korea has tripled over the last decade. We conducted a community based 1:1 matched case-control study to assess the effectiveness of one MAV strain-based vaccine and three Oka strain-based vaccines licensed for use in Korea. All cases were children in Seoul, Korea with varicella who were reported to the National Notifiable Disease Surveillance System in Seoul during 2013. The controls were age-matched children with mumps or scarlet fever but no history of varicella. We included 537 cases and 537 controls. The overall effectiveness of one dose of varicella vaccination was 13% (95% confidence interval [CI], -17.3-35.6). Of the four licensed varicella vaccines, only one was highly effective (88.9%; 95% CI, 52.1-97.4). The vaccine effectiveness for the other vaccines were 71.4% (95% CI, -37.5-94.1), -5% (95% CI, -61.9-31.9), and -100% (95% CI, -700-50.0). The overall effectiveness of vaccination was 75.8% (95% CI, 22.8-92.4) in the first year after vaccination and decreased thereafter; the effectiveness became -7.2% (95% CI, -130.9-59.2) in the fourth year after vaccination. Further studies are warranted to investigate reduced effectiveness of varicella vaccines in Korea.

Indexed as

Case-Control StudiesChickenpoxChickenpox VaccineChildChild, PreschoolFemaleHumansImmunization ProgramsInfantLogistic ModelsMaleRepublic of KoreaTreatment OutcomeChickenpox VaccineCase-Control StudyChickenpoxKoreaMatched Case-Control StudyVaccinationVaricella

Identifiers

PMID27822926
PMCPMC5102851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.