ReviewJournal of Korean medical science2016
Inhalation Lung Injury Associated with Humidifier Disinfectants in Adults.
Review in Journal of Korean medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Health Effects Associated With Humidifier Disinfectant Use: A Systematic Review for Exploration.Journal of Korean medical science · 2022Pooled it
- CRISPR-engineered human lung organoids with a biomolecular condensate reporter enable mechanistic toxicity monitoring.Materials today. Bio · 2026Article
- Pulmonary ultrasound-guided management of delayed pulmonary edema secondary to nitric acid fumes inhalation: a case report.BMC pulmonary medicine · 2025Article
- Evaluating Metabolic Signatures in the Serum of South Korean Patients with Humidifier Disinfectant-Associated Lung Injury Identified through Untargeted Metabolomics.Environmental health perspectives · 2025Article
- Evaluation of the Current Urgency-Based Lung Allocation System in Korea with Simulation of the Eurotransplant Lung Allocation Score.Yonsei medical journal · 2024Article
- Article
- Reduced Diffusing Capacity in Humidifier Disinfectant-Associated Asthma Versus Typical Asthma: A Retrospective Case Control Study.Journal of Korean medical science · 2022Article
- Disruption of Membrane Integrity as a Molecular Initiating Event Determines the Toxicity of Polyhexamethylene Guanidine Phosphate Depending on the Routes of Exposure.International journal of molecular sciences · 2022Article
- Integrative multi-omics approach for mechanism of humidifier disinfectant-associated lung injury.Clinical and translational medicine · 2021Article
- Transcriptomic Analysis of Polyhexamethyleneguanidine-Induced Lung Injury in Mice after a Long-Term Recovery.Toxics · 2021Article
- Increased plastic pollution due to COVID-19 pandemic: Challenges and recommendations.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2021Review
- Comparison of Long Term Follow-up Chest CT Imaging in Adult and Pediatric Patients with Humidifier Disinfectant-related Lung Injury.Journal of Korean medical science · 2020Article
- Toxicity of humidifier disinfectant polyhexamethylene guanidine hydrochloride by two-week whole body-inhalation exposure in rats.Journal of toxicologic pathology · 2020Article
- The past, present, and future of humidifier disinfectant-associated interstitial lung diseases in children.Clinical and experimental pediatrics · 2020Article
- Problems with diagnostic criteria for humidifier disinfectant lung injury (HDLI): two cases of radiologically improved HDLI.Annals of occupational and environmental medicine · 2020Article
- Immunohistochemical characterization of oxidative stress in the lungs of rats exposed to the humidifier disinfectant polyhexamethylene guanidine hydrochloride.Journal of toxicologic pathology · 2019Article
- Psychological Responses among Humidifier Disinfectant Disaster Victims and Their Families.Journal of Korean medical science · 2019Article
- Humidifier Disinfectant-Associated Lung Injury: Six Years after the Tragic Event.Tuberculosis and respiratory diseases · 2017Review
- Humidifier disinfectant-associated specific diseases should be called together as "humidifier disinfectant syndrome".Environmental health and toxicology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We recently established a novel disease entity presented as progressive respiratory failure associated with the inhalation of humidifier disinfectants. In April 2011, we encountered a series of peripartum patients with complaints of respiratory distress of unknown etiology, which was an uncommon phenomenon. Accordingly, we created a multidisciplinary team comprising intensivists, radiologists, pathologists, epidemiologists, and the Korea Centers for Disease Control and Prevention (KCDC). Further, we defined the disease entity and performed a case-control study, epidemiologic investigation, and animal study to determine the etiology. The study findings indicated that the lung injury outbreak was related to the inhalation of humidifier disinfectants and showed that household chemical inhalation can cause severe respiratory failure. Following the withdrawal of humidifier disinfectants from the Korean market in 2012, no such cases were reported. This tragic event is a warning that appropriate safety regulations and monitoring for potential toxic household chemicals are critical to protect public health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.