ReviewObesity surgery2017
Pediatric Nonalcoholic Fatty Liver Disease: the Rise of a Lethal Disease Among Mexican American Hispanic Children.
Review in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Communicating incidental and reportable findings from research MRIs: considering factors beyond the findings in an underrepresented pediatric population.BMC medical research methodology · 2021Trial
- Sex as a moderator of body composition following a randomized controlled lifestyle intervention among Latino youth with obesity.Pediatric obesity · 2020Trial
- Diagnostic BMI and Induction Therapy Weight Change Associated With Hepatotoxicity in Pediatric Patients With Acute Lymphoblastic Leukemia.Cancer medicine · 2026Article
- Renal impairment is prevalent in pediatric NAFLD/MASLD and associated with disease severity.Journal of pediatric gastroenterology and nutrition · 2024Article
- Presence of Alpha 1 Antitrypsin Risk Variants is Not Associated With Histologic Severity of Pediatric NAFLD.Journal of pediatric gastroenterology and nutrition · 2023Article
- Review
- Perinatal High-Salt Diet Induces Gut Microbiota Dysbiosis, Bile Acid Homeostasis Disbalance, and NAFLD in Weanling Mice Offspring.Nutrients · 2021Article
- Review
- Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates.International journal of biological sciences · 2019Review
- Microarray Expression Profiling and Raman Spectroscopy Reveal Anti-Fatty Liver Action of Berberine in a Diet-Induced Larval Zebrafish Model.Frontiers in pharmacology · 2019Article
- Relationship between nonalcoholic fatty liver disease and bone mineral density in adolescents with obesity: a meta-analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Review
- Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish.Frontiers in endocrinology · 2018Article
- Obese children with fatty liver: Between reality and disease mongering.World journal of gastroenterology · 2017Review
- Pediatric Non-Alcoholic Fatty Liver Disease.Children (Basel, Switzerland) · 2017Review
- Obesity and Obesity Related Diseases, Sugar Consumption and Bad Oral Health: A Fatal Epidemic Mixtures: The Pediatric and Odontologist Point of View.Translational medicine @ UniSa · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hispanic children of Mexican origin have a high incidence of NAFLD. Susceptibility has been linked to a combination of factors including an increasing epidemic of obesity in children and adolescents, an allele substitution in the PNPLA3 gene that reduces hepatic lipid catabolism, and an altered microbiome that may increase hepatic endotoxins. The combination of NAFLD and portal vein toxins secondary to an indigenous gut microbiome appear to lead to the early occurrence of NASH, which progresses to cirrhosis and early hepatocellular carcinoma. Early detection and treatment of hepatic changes are needed. Given the success of gastric bypass in reducing body weight, modifying the gut microbiome, and improving NAFLD/NASH in adults, a trial of gastric bypass in predisposed pediatric candidates should be undertaken.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.