Evidence map›Paper›PMID 27822731›Full record

ArticleMycopathologia2017

Are Cystic Fibrosis Aspergillus fumigatus Isolates Different? Intermicrobial Interactions with Pseudomonas.

Hasan Nazik, Richard B Moss, Vyshnavi Karna, Karl V Clemons, Niaz Banaei, Kevin Cohen, Varun Choudhary, David A Stevens

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Interactions between Bacteria andJournal of fungi (Basel, Switzerland) · 2023
    Review
  2. Intestinal bacteria-a powerful weapon for fungal infections treatment.Frontiers in cellular and infection microbiology · 2023
    Review
  3. Review
  4. Interactions between invasive fungi and symbiotic bacteria.World journal of microbiology & biotechnology · 2020
    Review
  5. Journal of fungi (Basel, Switzerland) · 2020
    Article
  6. Review of PotentialJournal of fungi (Basel, Switzerland) · 2020
    Review
  7. Review
  8. Article
  9. Interactions ofFrontiers in microbiology · 2018
    Article
  10. Interaction betweenPeerJ · 2018
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hasan NazikCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA.
Richard B MossDivision of Pulmonology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Vyshnavi KarnaCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA.
Karl V ClemonsCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA.
Niaz BanaeiDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Kevin CohenCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA.
Varun ChoudharyCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA.
David A StevensCalifornia Institute for Medical Research, 2260 Clove Dr., San Jose, CA, 95128, USA. stevens@stanford.edu.ORCID http://orcid.org/0000-0002-5861-5716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa and Aspergillus fumigatus are the leading bacterial and fungal pathogens in cystic fibrosis (CF). We have shown that Af biofilms are susceptible to Pseudomonas, particularly CF phenotypes. Those studies were performed with a reference virulent non-CF Aspergillus. Pseudomonas resident in CF airways undergo profound genetic and phenotypic adaptations to the abnormal environment. Studies have also indicated Aspergillus from CF patients have unexpected profiles of antifungal susceptibility. This would suggest that Aspergillus isolates from CF patients may be different or altered from other clinical isolates. It is important to know whether Aspergillus may also be altered, as a result of that CF environment, in susceptibility to Pseudomonas. CF Aspergillus proved not different in that susceptibility.

Indexed as

Microbial InteractionsAntifungal AgentsAspergillosisAspergillus fumigatusBiofilmsCystic FibrosisHumansMicrobial ViabilityPseudomonas aeruginosaAntifungal AgentsAspergillusBiofilmCystic fibrosisIntermicrobial interactionPseudomonas

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.