ReviewEndocrine2017
The influence of phthalates and bisphenol A on the obesity development and glucose metabolism disorders.
Review in Endocrine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 5 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- Ultra-processed food consumption and increased risk of metabolic syndrome: a systematic review and meta-analysis of observational studies.Frontiers in nutrition · 2023Pooled it
- Leukocyte telomere length and obesity in children and adolescents: A systematic review and meta-analysis.Frontiers in genetics · 2022Pooled it
- Exposure to endocrine-disrupting chemicals and anthropometric measures of obesity: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Systematic review and meta-analysis on the association between phthalates exposure and insulin resistance.Environmental science and pollution research international · 2019Pooled it
- Bisphenol A exposure and type 2 diabetes mellitus risk: a meta-analysis.BMC endocrine disorders · 2018Pooled it
- Metabolism-disrupting compounds and metabolic health during the menopausal transition: a narrative review.International journal of obesity (2005) · 2026Review
- Real-Life Metal Cocktail Induced Pancreatic Alterations in Rats: Influence of Sex and Exposure Duration.International journal of molecular sciences · 2026Article
- Exposure to phthalate and phenol mixtures and obesity in children and adolescents: the dominant role of bisphenol A.Lipids in health and disease · 2026Article
- Association of PFAS, Metals, Phthalate and Organophosphate Metabolites with Depression Among U.S. Adults.International journal of environmental research and public health · 2026Article
- Are all ultra-processed foods created equal? Relevance of food processing and nutritional quality.European journal of epidemiology · 2025Article
- Identification and Characterization of a Novel Di-(2-ethylhexyl) Phthalate Hydrolase from a Marine Bacterial StrainInternational journal of molecular sciences · 2025Article
- The relationship between metabolic syndrome and environmental endocrine disruptors: A systematic review and meta-analysis.iScience · 2025Article
- Targeting ultra-processed foods for prevention of type 2 diabetes: state of the evidence and future directions.Diabetologia · 2025Review
- LOW-RANK LONGITUDINAL FACTOR REGRESSION WITH APPLICATION TO CHEMICAL MIXTURES.The annals of applied statistics · 2025Article
- Impact of Ex Vivo Bisphenol A Exposure on Gut Microbiota Dysbiosis and Its Association with Childhood Obesity.Journal of xenobiotics · 2025Article
- Endocrine Disruptors in Child Obesity and Related Disorders: Early Critical Windows of Exposure.Current nutrition reports · 2025Review
- Comparing phthalate exposure between bottlenose dolphins (Frontiers in Marine Science · 2025Article
- Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025Review
- Endocrine disruptors, insulin resistance, and diabetes.Turkish journal of medical sciences · 2025Review
- Investigation of protective effects of rutin\cyclodextrin inclusion complex against testicular damage caused by diisononyl phthalate in rats.Iranian journal of basic medical sciences · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of obesity and type 2 diabetes mellitus epidemics presents a great health problem worldwide. Beside the changes in diet and decreased physical activity, there is growing interest in endocrine disrupting chemicals that may have effects on these conditions. Among them, the role of certain phthalates and bisphenol A is confirmed. We have summarized the existing literature on this issue including cross-sectional, follow up epidemiological studies and in vivo and in vitro studies. Most data support the effects of bisphenol A and some phthalates, such as di-2-ethyl-hexyl phthalate, diethyl phthalate, dibuthyl phthalate, dimethyl phthalate, dibenzyl phthalate, diisononyl phthalate and others on the development obesity and type 2 diabetes mellitus. These endocrine disrupting chemicals interfere with different cell signaling pathways involved in weight and glucose homeostasis. Since the data are rather inconsistent, there is a need for new, well-designed prospective studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.