Evidence map›Paper›PMID 27822512›Full record

ArticlemSystems

ADAGE-Based Integration of Publicly Available

Jie Tan, John H Hammond, Deborah A Hogan, Casey S Greene

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 137 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Microbiology spectrum · 2024
    Article
  5. Article
  6. Article
  7. RNA-Seq Data Analysis.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Machine Learning in Drug Discovery: A Review.Artificial intelligence review · 2022
    Article
  20. Using genome-wide expression compendia to study microorganisms.Computational and structural biotechnology journal · 2022
    Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jie TanDepartment of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
John H HammondDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Casey S GreeneDepartment of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-8713-9213
Dartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2013 to 2017
$6.1M
Host-associated regulation of P. aeruginosa colonization and virulenceR01AI091702 · NIAID · DARTMOUTH COLLEGE · PI HOGAN, DEBORAH A · 2011 to 2015
$2.0M
NCI NIH HHS P30 CA023108NIAID NIH HHS R01 AI091702NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

The increasing number of genome-wide assays of gene expression available from public databases presents opportunities for computational methods that facilitate hypothesis generation and biological interpretation of these data. We present an unsupervised machine learning approach, ADAGE (

Indexed as

bioinformaticsdata integrationdenoising autoencodersgene expressiongenomics

Identifiers

PMID27822512
PMCPMC5069748
OpenAlexW2259632819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.