Evidence map›Paper›PMID 27822493›Full record

SynthesiseNeuro

Two Distinct Scene-Processing Networks Connecting Vision and Memory.

Christopher Baldassano, Andre Esteva, Li Fei-Fei, Diane M Beck

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 143 citations in OpenAlex.

  1. Article
  2. Article
  3. Post-saccadic disruption of semantic category information in naturalistic scenes.Cortex; a journal devoted to the study of the nervous system and behavior · 2026
    Article
  4. Effects of age on memory-related category-selective connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  5. Article
  6. Article
  7. Article
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  9. Cognitive maps for hierarchical spaces in the human brain.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. The Neural Underpinnings of Aphantasia: A Case Study of Identical Twins.bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christopher BaldassanoDepartment of Computer Science, Stanford University , Stanford, California 94305.ORCID 0000-0003-3540-5019
Andre EstevaDepartment of Electrical Engineering, Stanford University , Stanford, California 94305.
Li Fei-FeiDepartment of Computer Science, Stanford University , Stanford, California 94305.
Diane M BeckDepartment of Psychology, University of Illinois at Urbana-Champaign, Champaign, Illinois 61820; Beckman Institute, University of Illinois at Urbana-Champaign, Champaign, Illinois 61820.ORCID 0000-0001-9802-5828
Stanford University · USUniversity of Illinois Urbana-Champaign · US

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

A number of regions in the human brain are known to be involved in processing natural scenes, but the field has lacked a unifying framework for understanding how these different regions are organized and interact. We provide evidence from functional connectivity and meta-analyses for a new organizational principle, in which scene processing relies upon two distinct networks that split the classically defined parahippocampal place area (PPA). The first network of strongly connected regions consists of the occipital place area/transverse occipital sulcus and posterior PPA, which contain retinotopic maps and are not strongly coupled to the hippocampus at rest. The second network consists of the caudal inferior parietal lobule, retrosplenial complex, and anterior PPA, which connect to the hippocampus (especially anterior hippocampus), and are implicated in both visual and nonvisual tasks, including episodic memory and navigation. We propose that these two distinct networks capture the primary functional division among scene-processing regions, between those that process visual features from the current view of a scene and those that connect information from a current scene view with a much broader temporal and spatial context. This new framework for understanding the neural substrates of scene-processing bridges results from many lines of research, and makes specific functional predictions.

Indexed as

AdultBrainConnectomeDatasets as TopicFemaleHumansInternetMagnetic Resonance ImagingMaleMemoryNeural PathwaysPattern Recognition, VisualRestSpatial NavigationYoung Adultmemorynetworksscenevision

Identifiers

PMID27822493
PMCPMC5075944
OpenAlexW2951137108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.