ArticleResearch and reports in urology2016
Association of prostate volume with incidence and aggressiveness of prostate cancer.
Article in Research and reports in urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Predictive factors of incidental prostate cancer in patients undergoing surgery for presumed benign prostatic hyperplasia: an updated systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- MRI determined prostate volume and the incidence of prostate cancer on MRI-fusion biopsy: a systemic review of reported data for the last 20 years.International urology and nephrology · 2022Pooled it
- Association between prostate size and the incidence of prostate cancer: a meta-analysis and review for urologists and clinicians.International urology and nephrology · 2021Pooled it
- mpMRI-Based Risk Estimation to Optimize Prostate Cancer Patient Selection for Active Surveillance.Cancers · 2026Article
- Urinary Epithelial Cell Adhesion Molecule (EpCAM) as a Noninvasive Biomarker for Detecting Clinically Significant Prostate Cancer in Men With Equivocal PSA Levels.BioMed research international · 2026Article
- Influence of Prostate Volume on Targeted Biopsy Outcomes and PI-RADS Predictive Value for Significant Prostate Cancer.Journal of clinical medicine · 2025Article
- Prognostic value of central gland volume on MRI for biochemical recurrence after prostate radiotherapy.Abdominal radiology (New York) · 2025Article
- Analysis of risk factors for positive margins in robot-assisted laparoscopic radical prostatectomy with Retzius-sparing (RS-RARP).World journal of surgical oncology · 2025Article
- The Correlation Between Body Mass Index and Prostate Volume: A Retrospective Analysis of Pre and Postoperative Measurements in Prostate Cancer Patients.The Prostate · 2025Observational
- Correlation of Prostate-Specific Antigen (PSA), Prostate Volume, and Histology in Ugandan Males.Cureus · 2025Article
- Personalized prostate biopsy protocols: enhancing cancer detection through tailored approaches-a narrative review.Translational andrology and urology · 2025Review
- Comparison of data fusion strategies for automated prostate lesion detection using mpMRI correlated with whole mount histology.Radiation oncology (London, England) · 2024Article
- Computerized metric assessment of glandular tissue volume within the peripheral zone of the prostate using combined magnetic resonance imaging and histopathology: Possible pathophysiological implications on prostate cancer development.Investigative and clinical urology · 2024Article
- Prioritizing precision: detection of prostate cancer using mri guided fusion needle biopsy across the pennsylvania urologic regional collaborative.American journal of clinical and experimental urology · 2024Article
- The impact of pre-processing and disease characteristics on reproducibility of T2-weighted MRI radiomics features.Magma (New York, N.Y.) · 2023Article
- Prostate Region-Wise Imaging Biomarker Profiles for Risk Stratification and Biochemical Recurrence Prediction.Cancers · 2023Article
- The Impact of Prostate Volume on the Prostate Imaging and Reporting Data System (PI-RADS) in a Real-World Setting.Diagnostics (Basel, Switzerland) · 2023Article
- Association between prostate size and glandular tissue volume of the peripheral zone via novel combined MRI and histopathology: possible pathophysiological implications on prostate cancer development.International urology and nephrology · 2023Article
- Clinical Significance of Preoperative Assessment of Intravesical Prostatic Protrusion in Radical Prostatectomy.Journal of Cancer · 2023Article
- Predictors of Clinically Significant Prostate Cancer in Patients with PIRADS Categories 3-5 Undergoing Magnetic Resonance Imaging-Ultrasound Fusion Biopsy of the Prostate.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate the possible correlation between prostate volume and aggressiveness and incidence of prostate cancer (PCa). PATIENTS AND
methodsA chart review of a cohort of 448 consecutive prostate biopsy-naive men was performed. These men underwent at least a 12-core biopsy at our institution due to increased prostate-specific antigen serum levels (>4 ng/mL) and/or suspicious findings on digital rectal examination during the period between 2008 and 2013. Transrectal ultrasound was used to determine the prostate volume.
resultsThe positive biopsy rate was 66% for patients with a prostate volume of ≤35 cc and 40% for patients with a prostate volume of ≥65 cc (
conclusionThese results suggest that there may be an association between prostate volume and the incidence and aggressiveness of PCa. The larger the prostate, the lower the positive biopsy rate for PCa and the lower the Gleason score.
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