Evidence map›Paper›PMID 27822412›Full record

ArticleAmerican journal of cancer research2016

Regulation of p27

Chuang Sun, Gaohang Wang, Katharine H Wrighton, Han Lin, Zhou Songyang, Xin-Hua Feng, Xia Lin

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  3. Overexpression ofTranslational lung cancer research · 2025
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  6. Review
  7. Biological Evaluation of Dinuclear Platinum(II) Complexes with AromaticInternational journal of molecular sciences · 2024
    Review
  8. Article
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  12. Article
  13. Article
  14. Lymphostatin, a virulence factor of attaching and effacingFrontiers in cellular and infection microbiology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chuang SunDepartment of Molecular Physiology and Biophysics, Baylor College of MedicineHouston, TX 77030, USA; Michael E. DeBakey Department of Surgery, Baylor College of MedicineHouston, TX 77030, USA.
Gaohang WangMichael E. DeBakey Department of Surgery, Baylor College of MedicineHouston, TX 77030, USA; Department of Molecular & Cellular Biology, Baylor College of MedicineHouston, TX 77030, USA; Life Sciences Institute and Innovation Center for Cell Signaling, Zhejiang UniversityHangzhou, Zhejiang 310058, China.
Katharine H WrightonMichael E. DeBakey Department of Surgery, Baylor College of MedicineHouston, TX 77030, USA; Department of Molecular & Cellular Biology, Baylor College of MedicineHouston, TX 77030, USA; Present address: Nature Reviews JournalsPorters South, 4 Crinan Street, London, N1 9XW, United Kingdom.
Han LinDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine Houston, TX 77030, USA.
Zhou SongyangDepartment of Biochemistry and Molecular Biology, Baylor College of Medicine Houston, TX 77030, USA.
Xin-Hua FengDepartment of Molecular Physiology and Biophysics, Baylor College of MedicineHouston, TX 77030, USA; Michael E. DeBakey Department of Surgery, Baylor College of MedicineHouston, TX 77030, USA; Department of Molecular & Cellular Biology, Baylor College of MedicineHouston, TX 77030, USA; Life Sciences Institute and Innovation Center for Cell Signaling, Zhejiang UniversityHangzhou, Zhejiang 310058, China.
Xia LinMichael E. DeBakey Department of Surgery, Baylor College of Medicine Houston, TX 77030, USA.
Baylor College of Medicine · USMichael E. DeBakey VA Medical Center · US

Funding

Regulation of TGF-beta Receptor Signaling by HSP90R01GM063773 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI FENG, XIN-HUA · 2001 to 2010
$2.3M
Tumor Suppressor Function of Smad4 by UbiquitinR01CA108454 · NCI · BAYLOR COLLEGE OF MEDICINE · PI FENG, XIN-HUA · 2004 to 2010
$1.8M
Roles of Smad1 Dephosphorylation in Osteoblast DifferentiationR01AR053591 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI FENG, XIN-HUA · 2008 to 2012
$1.5M
Regulation of SMAD2 Signaling by SMP1 PhosphataseR01DK073932 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI LIN, XIA · 2005 to 2008
$1.1M
NCI NIH HHS R01 CA108454NIAMS NIH HHS R01 AR053591NIDDK NIH HHS R01 DK073932NIGMS NIH HHS R01 GM063773
6 · The paper itself

Abstract

The cell cycle, an essential process leading to the cell division, is stringently controlled by the key cell cycle regulators, cyclin-CDK complexes, whose activity is further regulated by a variety of mechanisms. p27

Indexed as

cell cyclep27PPM1Gprotein phosphatase

Identifiers

PMID27822412
PMCPMC5088286
OpenAlexW2564460377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.