Evidence map›Paper›PMID 27822211›Full record

ArticleFrontiers in immunology2016

CD4

John Zaunders, Mark Danta, Michelle Bailey, Gerald Mak, Katherine Marks, Nabila Seddiki, Yin Xu, David J Templeton, David A Cooper, Mark A Boyd and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. CD73International journal of molecular sciences · 2021
    Article
  5. Article
  6. Article
  7. Possible clearance of transfusion-acquiredJournal of virus eradication · 2019
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Divergent Expression of CXCR5 and CCR5 on CD4Frontiers in immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

John ZaundersSt Vincent's Centre for Applied Medical Research, St Vincent's Hospital, Sydney, NSW, Australia; The Kirby Institute, The University of New South Wales, Sydney, NSW, Australia.
Mark DantaSt Vincent's Hospital, Clinical School , Sydney, NSW , Australia.
Michelle BaileyThe Kirby Institute, The University of New South Wales , Sydney, NSW , Australia.
Gerald MakSt Vincent's Hospital, Clinical School , Sydney, NSW , Australia.
Katherine MarksSt Vincent's Centre for Applied Medical Research, St Vincent's Hospital , Sydney, NSW , Australia.
Nabila SeddikiEquipe 16, INSERM U955, Créteil, France; Faculté de médecine, Université Paris Est, Créteil, France; Vaccine Research Institute (VRI), Créteil, France.
Yin XuThe Kirby Institute, The University of New South Wales , Sydney, NSW , Australia.
David J TempletonThe Kirby Institute, The University of New South Wales, Sydney, NSW, Australia; RPA Sexual Health, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
David A CooperSt Vincent's Centre for Applied Medical Research, St Vincent's Hospital, Sydney, NSW, Australia; The Kirby Institute, The University of New South Wales, Sydney, NSW, Australia.
Mark A BoydThe Kirby Institute, The University of New South Wales , Sydney, NSW , Australia.
Anthony D KelleherSt Vincent's Centre for Applied Medical Research, St Vincent's Hospital, Sydney, NSW, Australia; The Kirby Institute, The University of New South Wales, Sydney, NSW, Australia.
Kersten K KoelschThe Kirby Institute, The University of New South Wales , Sydney, NSW , Australia.
St Vincent's Hospital Sydney · AUUNSW Sydney · AUSt Vincent's Hospital · AUInserm · FRRoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisruption of gastrointestinal tract epithelial and immune barriers contribute to microbial translocation, systemic inflammation, and progression of HIV-1 infection. Antiretroviral therapy (ART) may lead to reconstitution of CD4

methodsTwenty-three HIV

resultsNo significant differences in the number of recovered epithelial cells were observed between the two subject groups. However, the median TI CD4

conclusionWhile there were lower absolute CD4

Indexed as

CD4+ T lymphocytesgerminal centersgut-associated lymphoid tissueHIVIgA B cellsT follicular helper cells

Identifiers

PMID27822211
PMCPMC5075890
OpenAlexW2537711516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.