Evidence map›Paper›PMID 27822040›Full record

ArticleInternational journal of nanomedicine

Raspberry-like poly(γ-glutamic acid) hydrogel particles for pH-dependent cell membrane passage and controlled cytosolic delivery of antitumor drugs.

Sun-Hee Cho, Ji Hyeon Hong, Young-Woock Noh, Eunji Lee, Chang-Soo Lee, Yong Taik Lim

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sun-Hee ChoSKKU Advanced Institute of Nanotechnology, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do.
Ji Hyeon HongGraduate School of Analytical Science and Technology, Chungnam National University.
Young-Woock NohSKKU Advanced Institute of Nanotechnology, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do.
Eunji LeeGraduate School of Analytical Science and Technology, Chungnam National University.
Chang-Soo LeeHazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Republic of Korea.
Yong Taik LimSKKU Advanced Institute of Nanotechnology, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do.
Chungnam National University · KRInstitute of Nanotechnology · GBKorea Research Institute of Bioscience and Biotechnology · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, we synthesized bioderived poly(amino acid) hydrogel particles that showed pH-dependent membrane-disrupting properties and controlled cytosolic delivery of antitumor drugs. Poly(γ-glutamic acid) (γ-PGA) that has been produced extensively using bacteria, especially those of

Indexed as

Drug Delivery SystemsAnimalsAntibiotics, AntineoplasticCell MembraneCytosolDoxorubicinDrug CarriersErythrocytesFemaleFlow CytometryHemolysisHumansHydrogel, Polyethylene Glycol DimethacrylateHydrogen-Ion ConcentrationNanoparticlesPolyglutamic AcidAntibiotics, AntineoplasticDoxorubicinDrug CarriersHydrogel, Polyethylene Glycol Dimethacrylatepoly(gamma-glutamic acid)Polyglutamic Acidantitumorcontrolled releaseendosomal escapehydrogel particles

Identifiers

PMID27822040
PMCPMC5089826
OpenAlexW2543458228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.