Evidence map›Paper›PMID 27822017›Full record

ArticlePatient preference and adherence2016

Treatment satisfaction in cystic fibrosis: early patient experience with tobramycin inhalation powder.

Jonathan Greenberg, Jacqueline B Palmer, Wing W Chan, Catherine E Correia, Diane Whalley, Paul Shannon, Gregory S Sawicki

Abstract read
In one paragraph

Article in Patient preference and adherence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan GreenbergDivision of Respiratory Diseases, Boston Children's Hospital, Boston, MA.
Jacqueline B PalmerNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Wing W ChanNovartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Catherine E CorreiaDivision of Respiratory Diseases, Boston Children's Hospital, Boston, MA.
Diane WhalleyRTI Health Solutions, Manchester, UK.
Paul ShannonRTI Health Solutions, Manchester, UK.
Gregory S SawickiDivision of Respiratory Diseases, Boston Children's Hospital, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assessed treatment satisfaction of cystic fibrosis (CF) patients in a routine clinical setting for tobramycin inhalation powder (TIP), the first dry powder-inhaled antibiotic for

methodsCF patients aged 6 years or older treated with at least one cycle of TIP completed a web survey on experience with TIP, including the Treatment Satisfaction Questionnaire for Medication (TSQM). Regression analysis determined the factors associated with TSQM global satisfaction.

resultsEighty patients (mean age ± standard deviation: 24.4±9.4 years; 57.5% female; mean forced expiratory volume in 1 second ± standard deviation: 67.1%±27.3% predicted) completed the survey. The majority expressed satisfaction with TIP's administration time (100%), time to clean (97.1%), portability (97.1%), and ease of use (94.3%). Effectiveness was significantly associated with TSQM global satisfaction (regression

conclusionPatient preferences for TIP were based on administration time and ease of use. Global satisfaction was related to greater patient-perceived effectiveness.

Indexed as

cystic fibrosisdry powder inhalerspatient satisfactiontobramycin

Identifiers

PMID27822017
PMCPMC5087789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.