Evidence map›Paper›PMID 27821737›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability.

Edgar Buhl, Adam Bradlaugh, Maite Ogueta, Ko-Fan Chen, Ralf Stanewsky, James J L Hodge

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Function and regulation of the insect NaCCC2 sodium transport proteins.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2024
    Article
  3. Review
  4. Article
  5. Frontiers in neuroscience · 2023
    Article
  6. Adaptation ofJournal of biological rhythms · 2022
    Article
  7. Article
  8. DYRK1a Inhibitor Mediated Rescue ofFrontiers in pharmacology · 2022
    Article
  9. Article
  10. Article
  11. High-Frequency Neuronal Bursting is Essential for Circadian and Sleep Behaviors inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. A Drosophila Model of Essential Tremor.Scientific reports · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edgar BuhlSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, United Kingdom; e.buhl@bristol.ac.uk r.stanewsky@ucl.ac.uk.ORCID 0000-0003-1274-5870
Adam BradlaughDepartment of Cell and Developmental Biology, University College London, London WC1E 6DE, United Kingdom.
Maite OguetaDepartment of Cell and Developmental Biology, University College London, London WC1E 6DE, United Kingdom.
Ko-Fan ChenInstitute of Neurology, University College London, London WC1N 3BG, United Kingdom.
Ralf StanewskyDepartment of Cell and Developmental Biology, University College London, London WC1E 6DE, United Kingdom; e.buhl@bristol.ac.uk r.stanewsky@ucl.ac.uk.
James J L HodgeSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol BS8 1TD, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/J017221/1Biotechnology and Biological Sciences Research Council BB/J018589/2
6 · The paper itself

Abstract

We have characterized a light-input pathway regulating Drosophila clock neuron excitability. The molecular clock drives rhythmic electrical excitability of clock neurons, and we show that the recently discovered light-input factor Quasimodo (Qsm) regulates this variation, presumably via an Na

Indexed as

LightAllelesAnimalsBehavior, AnimalCircadian ClocksDrosophila melanogasterDrosophila Proteinsgamma-Aminobutyric AcidGene Knockdown TechniquesGenotypeGPI-Linked ProteinsIon Channel GatingModels, BiologicalNeuronsProtein BindingDrosophila Proteinsgamma-Aminobutyric AcidGPI-Linked ProteinsQSM protein, Drosophilacircadian rhythmsGABA reversal potentiallight inputmembrane excitabilitypotassium currents

Identifiers

PMID27821737
PMCPMC5127355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.