Evidence map›Paper›PMID 27821629›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Polyomavirus Reactivation and Immune Responses to Kidney-Specific Self-Antigens in Transplantation.

Michael E Seifert, Muthukumar Gunasekaran, Timothy A Horwedel, Reem Daloul, Gregory A Storch, Thalachallour Mohanakumar, Daniel C Brennan

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions for BK virus infection in kidney transplant recipients.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Subclinical inflammation phenotypes and long-term outcomes after pediatric kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Trial
  3. Review
  4. Article
  5. A multicenter prospective study to define the natural history of BK viral infections in kidney transplantation.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Observational
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. WNT pathway signaling is associated with microvascular injury and predicts kidney transplant failure.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019
    Article
  12. Article
  13. Article
  14. Neutralizing Antibody-Mediated Response and Risk of BK Virus-Associated Nephropathy.Journal of the American Society of Nephrology : JASN · 2018
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael E SeifertDepartment of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama; mseifert@peds.uab.edu.
Muthukumar GunasekaranSurgery, and.
Timothy A HorwedelRenal Division, Department of Medicine, Washington University, St. Louis, Missouri; and.
Reem DaloulRenal Division, Department of Medicine, Washington University, St. Louis, Missouri; and.
Gregory A StorchDepartments of Pediatrics.
Thalachallour MohanakumarSurgery, and.
Daniel C BrennanRenal Division, Department of Medicine, Washington University, St. Louis, Missouri; and.

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Washington University Institute of Clinical and Translational Sciences (KL2)KL2RR024994 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$8.6M
Novel Biomarkers of Angiogenesis and Vascular Injury in Chronic RejectionK23DK101690 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SEIFERT, MICHAEL EDWARD · 2015 to 2017
$555k
NCATS NIH HHS KL2 TR000450NCATS NIH HHS UL1 TR000448NCRR NIH HHS KL2 RR024994NIDDK NIH HHS K23 DK101690NIDDK NIH HHS L40 DK099748
6 · The paper itself

Abstract

Humoral immune responses against donor antigens are important determinants of long-term transplant outcomes. Reactivation of the polyomavirus BK has been associated with

Indexed as

AutoantigensKidney TransplantationCase-Control StudiesCohort StudiesFemaleHumansImmunosuppression TherapyKidneyMaleMiddle AgedPolyomavirusPolyomavirus InfectionsPostoperative ComplicationsRetrospective StudiesTime FactorsTreatment OutcomeAutoantigensimmunosuppressionkidney transplantationtransplant outcomesvirology

Identifiers

PMID27821629
PMCPMC5373442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.