Evidence map›Paper›PMID 27821585›Full record

ArticleInfection and immunity2017

Listeria monocytogenes-Induced Cell Death Inhibits the Generation of Cell-Mediated Immunity.

Erin Theisen, John-Demian Sauer

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

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  5. Frontiers in veterinary science · 2024
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  8. Review
  9. Article
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  11. Article
  12. Review
  13. An Inducible Cre-Toxins · 2020
    Article
  14. Current clinical microbiology reports · 2019
    Article
  15. A Potent and Effective SuicidalInfection and immunity · 2019
    Article
  16. Cyclooxygenase-1 and -2 Play Contrasting Roles inJournal of immunology (Baltimore, Md. : 1950) · 2018
    Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erin TheisenDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
John-Demian SauerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA sauer3@wisc.edu.ORCID http://orcid.org/0000-0001-9367-794X
University of Wisconsin–Madison · US

Funding

INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Modulating the Inflammasome to Generate Robust Cell Mediated ImmunityR01CA188034 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2015 to 2019
$1.7M
Cell-Mediated Immunity Following Listeria monocytogenes Induced Inflammasome ActivationF30CA210912 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI THEISEN, ERIN MARIE · 2016 to 2018
$100k
NCI NIH HHS F30 CA210912NCI NIH HHS R01 CA188034NIAID NIH HHS HHSN272201300006CNIGMS NIH HHS T32 GM008692
6 · The paper itself

Abstract

The influence of cell death on adaptive immunity has been studied for decades. Despite these efforts, the intricacies of how various cell death pathways shape immune responses in the context of infection remain unclear, particularly with regard to more recently discovered pathways such as pyroptosis. The emergence of Listeria monocytogenes as a promising immunotherapeutic platform demands a thorough understanding of how cell death induced in the context of infection influences the generation of CD8

Indexed as

AnimalsCD8 AntigensCD8-Positive T-LymphocytesCell DeathFemaleImmunity, CellularListeria monocytogenesListeriosisMiceMice, Inbred C57BLPyroptosisCD8 Antigensapoptosiscell deathimmunotherapyinflammasomeListeria monocytogenes

Identifiers

PMID27821585
PMCPMC5203660
OpenAlexW2555805983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.