Evidence map›Paper›PMID 27821578›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2016

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

Andrea Pennati, Spencer Ng, Yuanqiang Wu, Jordan R Murphy, Jiusheng Deng, Srikant Rangaraju, Seneshaw Asress, Jennifer L Blanchfield, Brian Evavold, Jacques Galipeau

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 55 citations in OpenAlex.

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  10. GαJournal of the Endocrine Society · 2024
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  16. Risk Factors from Pregnancy to Adulthood in Multiple Sclerosis Outcome.International journal of molecular sciences · 2022
    Review
  17. Frontiers in immunology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Andrea PennatiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health and University of Wisconsin Carbone Cancer Center, Madison, Wisconsin 53706.ORCID 0000-0001-6211-7480
Spencer NgDepartments of Hematology and Medical Oncology.
Yuanqiang WuNeurology, and.
Jordan R MurphyDepartments of Hematology and Medical Oncology.
Jiusheng DengDepartments of Hematology and Medical Oncology.ORCID 0000-0003-1758-3778
Srikant RangarajuMicrobiology and Immunology, Emory University, Atlanta, Georgia 30322, and.ORCID 0000-0003-2765-1500
Seneshaw AsressMicrobiology and Immunology, Emory University, Atlanta, Georgia 30322, and.
Jennifer L BlanchfieldDepartment of Oncology, Second Xiangya Hospital, Changsha 410011, Hunan, People's Republic of China.ORCID 0000-0002-9461-9431
Brian EvavoldDepartment of Oncology, Second Xiangya Hospital, Changsha 410011, Hunan, People's Republic of China.
Jacques GalipeauDepartment of Medicine, University of Wisconsin School of Medicine and Public Health and University of Wisconsin Carbone Cancer Center, Madison, Wisconsin 53706, jgalipeau@wisc.edu.ORCID 0000-0002-9374-1996
Central South University · CNEmory University · USUniversity of Wisconsin Carbone Cancer Center · USNeurology, Inc · US

Funding

The Emory Alzheimer's Disease CenterP50AG025688 · NIA · EMORY UNIVERSITY · PI LEVEY, ALLAN I · 2005 to 2019
$25.7M
Inducible B-regulatory cells (iBREGs) for treatment of Multiple SclerosisR01AI093881 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GALIPEAU, JACQUES · 2012 to 2016
$1.9M
NIAID NIH HHS R01 AI093881NIA NIH HHS P50 AG025688
6 · The paper itself

Abstract

Although B cells are traditionally known for their role in propagating proinflammatory immune responses, their immunosuppressive effects have only recently begun to be appreciated. How these regulatory B cells (B SIGNIFICANCE STATEMENT: Although B cells are traditionally known for their role in propagating proinflammatory immune responses, their immunosuppressive effects have only recently begun to be appreciated. How regulatory B cells (B

Indexed as

Adoptive TransferAnimalsB-Lymphocytes, RegulatoryCD4-Positive T-LymphocytesChild, PreschoolCoculture TechniquesEncephalomyelitis, Autoimmune, ExperimentalForkhead Transcription FactorsHumansInterleukin-10LeukocytesLymph NodesMiceMice, Inbred C57BLMultiple SclerosisSpleenForkhead Transcription FactorsFoxp3 protein, mouseIL10 protein, mouseInterleukin-10

Identifiers

PMID27821578
PMCPMC5157105
OpenAlexW2557210462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.