Evidence map›Paper›PMID 27821536›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2016

Stochastic left-right neuronal asymmetry in Caenorhabditis elegans.

Amel Alqadah, Yi-Wen Hsieh, Rui Xiong, Chiou-Fen Chuang

Open access · bronzeAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Analysis of biological networks using Krylov subspace trajectories.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. A universal transportin protein drives stochastic choice of olfactory neurons via specific nuclear import of aProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  15. Article
  16. Asymmetric development of the nervous system.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Review
  17. Article
  18. Introduction to provocative questions in left-right asymmetry.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amel AlqadahDepartment of Biological Sciences, University of Illinois at Chicago, IL 60607, USA.
Yi-Wen HsiehDepartment of Biological Sciences, University of Illinois at Chicago, IL 60607, USA.
Rui XiongDepartment of Biological Sciences, University of Illinois at Chicago, IL 60607, USA.
Chiou-Fen ChuangDepartment of Biological Sciences, University of Illinois at Chicago, IL 60607, USA chioufen.chuang@gmail.com.ORCID 0000-0001-7469-076X
Google (United States) · US

Funding

Specification of Stochastic Left-Right Asymmetric Neuronal Fates in C. elegansR01GM098026 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHUANG, CHIOU-FEN · 2012 to 2016
$1.5M
NIGMS NIH HHS R01 GM098026
6 · The paper itself

Abstract

Left-right asymmetry in the nervous system is observed across species. Defects in left-right cerebral asymmetry are linked to several neurological diseases, but the molecular mechanisms underlying brain asymmetry in vertebrates are still not very well understood. The Caenorhabditis elegans left and right amphid wing 'C' (AWC) olfactory neurons communicate through intercellular calcium signalling in a transient embryonic gap junction neural network to specify two asymmetric subtypes, AWC

Indexed as

Body PatterningCalcium SignalingGene Expression Regulation, DevelopmentalAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsGap JunctionsNervous SystemCaenorhabditis elegans ProteinsCaenorhabditis elegansneuronal asymmetrystochasticity

Identifiers

PMID27821536
PMCPMC5104506
OpenAlexW2551626179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.