Evidence map›Paper›PMID 27821456›Full record

ArticleAntimicrobial agents and chemotherapy2017

Carbapenem-Resistant Pseudomonas aeruginosa Bacteremia: Risk Factors for Mortality and Microbiologic Treatment Failure.

Deanna J Buehrle, Ryan K Shields, Lloyd G Clarke, Brian A Potoski, Cornelius J Clancy, M Hong Nguyen

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Beyond Resistance Genes:Life (Basel, Switzerland) · 2026
    Review
  4. Observational
  5. Predictors of Mortality inPathogens (Basel, Switzerland) · 2026
    Review
  6. Whole-genome sequencing reveals molecular characterization of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  7. Early risk stratification for carbapenem resistance amongFrontiers in cellular and infection microbiology · 2026
    Article
  8. Article
  9. Article
  10. Carbapenem-resistant bacteria in the environment.Arhiv za higijenu rada i toksikologiju · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Deanna J BuehrleDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ryan K ShieldsDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lloyd G ClarkeDepartment of Pharmacy & Therapeutics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Brian A PotoskiDepartment of Pharmacy & Therapeutics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Cornelius J ClancyDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA cjc76@pitt.edu.
M Hong NguyenDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Caspofungin pharmacokinetics-pharmacodynamics during intra-adbominal candidiasisK08AI114883 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIELDS, RYAN K · 2015 to 2019
$858k
NIAID NIH HHS K08 AI114883
6 · The paper itself

Abstract

We reviewed 37 patients treated for bacteremia due to carbapenem-resistant (CR) Pseudomonas aeruginosa Although 65% of isolates were multiple-drug resistant, therapeutic options were available, as all were susceptible to ≥1 antibiotic. A total of 92% of patients received active antimicrobial therapy, but only 57% received early active therapy (within 48 h). Fourteen-day mortality was 19%. Microbiologic failure occurred in 29%. The Pitt bacteremia score (P = 0.046) and delayed active therapy (P = 0.027) were predictive of death and microbiologic failure, respectively.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacteremiaCarbapenemsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedPseudomonas aeruginosaPseudomonas InfectionsRetrospective StudiesRisk FactorsAnti-Bacterial AgentsCarbapenemsbacteremiacarbapenem resistancemortalityPseudomonas aeruginosa

Identifiers

PMID27821456
PMCPMC5192105
OpenAlexW2550317740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.