Evidence map›Paper›PMID 27821452›Full record

ArticleAntimicrobial agents and chemotherapy2017

CTX-M-190, a Novel β-Lactamase Resistant to Tazobactam and Sulbactam, Identified in an Escherichia coli Clinical Isolate.

Zhen Shen, Baixing Ding, Yingmin Bi, Shi Wu, Su Xu, Xiaogang Xu, Qinglan Guo, Minggui Wang

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antimicrobial agents and chemotherapy · 2020
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Past and Present Perspectives on β-Lactamases.Antimicrobial agents and chemotherapy · 2018
    Review
  11. Article
  12. ESBL-producingFood safety (Tokyo, Japan) · 2017
    Review
  13. Genetic and Functional Characterization ofAntimicrobial agents and chemotherapy · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhen ShenInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Baixing DingInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Yingmin BiInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Shi WuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Su XuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Xiaogang XuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Qinglan GuoInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-2490-1201
Minggui WangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China mgwang@fudan.edu.cn.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel β-lactamase, CTX-M-190, derived from CTX-M-55 by a single substitution of Ser for Thr at position 133 (Ser133Thr), was identified in a natural Escherichia coli clinical isolate. CTX-M-190 exhibited potent hydrolytic activity against cefotaxime, with a k

Indexed as

Amino Acid SubstitutionAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-Lactam ResistanceCefotaximeCloning, MolecularEscherichia coliEscherichia coli InfectionsFemaleGene ExpressionHumansInhibitory Concentration 50Middle AgedPenicillanic AcidPlasmidsAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-LactamasesCefotaximePenicillanic AcidSulbactamTazobactamCTX-M-190Escherichia coliinhibitor-resistant β-lactamasesulbactamtazobactam

Identifiers

PMID27821452
PMCPMC5192109
OpenAlexW2555390787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.