ReviewEuropean journal of sport science2018
The 'sensory tolerance limit': A hypothetical construct determining exercise performance?
Review in European journal of sport science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of Transcranial Direct Current Stimulation on Upper Limb Muscle Strength and Endurance in Healthy Individuals: A Systematic Review and Meta-Analysis.Frontiers in physiology · 2022Pooled it
- Pooled it
- Differences in time to task failure and fatigability between children and young adults: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Non-local Muscle Fatigue Effects on Muscle Strength, Power, and Endurance in Healthy Individuals: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Acute pre-exercise oral intake of cacao polyphenols attenuates central fatigue development during sustained low-intensity ankle dorsiflexion exercise in healthy young male adults.Physiological reports · 2026Trial
- Five Weeks of Sprint Interval Training Increase Absolute Power Output Within Severe-Intensity Domain Without Altering Muscle Activation or Fatigability.European journal of sport science · 2026Trial
- Neuromuscular fatigue differences between prepubertal boys and men after maximal concentric versus eccentric isokinetic knee extensions.European journal of applied physiology · 2026Trial
- Caffeine intake reverses the impairment of sleep restriction on high-intensity exercise performance.European journal of applied physiology · 2026Trial
- The impact of acute blood-flow-restriction resistance exercise on somatosensory-evoked potentials in healthy adults.Experimental physiology · 2024Trial
- Activation of skeletal muscle mechanoreceptors and nociceptors reduces the exercise performance of the contralateral homologous muscles.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Trial
- Comparison of neuromuscular fatigability amplitude and etiologies between fatigued and non-fatigued cancer patients.European journal of applied physiology · 2024Trial
- Acute acetaminophen ingestion improves performance and muscle activation during maximal intermittent knee extensor exercise.European journal of applied physiology · 2018Trial
- Endurance, aerobic high-intensity, and repeated sprint cycling performance is unaffected by normobaric "Live High-Train Low": a double-blind placebo-controlled cross-over study.European journal of applied physiology · 2017Trial
- Delaying task failure in high-intensity exercise: a Pi-afferent-effort framework for targeted sports nutrition.Journal of the International Society of Sports Nutrition · 2026Review
- Ventilatory drive modulates the temporal evolution of multidimensional dyspnoea during constant-load exercise in healthy adults.European journal of applied physiology · 2026Article
- Cerebral oxygenation and skeletal muscle responses to time trial, maximal oxygen uptake and time to exhaustion exercise.Experimental physiology · 2026Article
- Physical and cognitive contributions to fatigue perception: The interplay between local muscle fatigue and sensory prediction error.iScience · 2026Article
- Task Failure in Endurance Sports: A Review.Sports medicine (Auckland, N.Z.) · 2026Review
- Effect of hypoxia on muscle activation at equivalent absolute and relative intensity during incremental and constant load exercise to task failure.Experimental physiology · 2026Article
- Examination of sex differences in fatigability, muscle oxygenation, and neuromuscular responses during low-intensity isometric handgrip exercise.European journal of applied physiology · 2026Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Neuromuscular fatigue compromises exercise performance and is determined by central and peripheral mechanisms. Interactions between the two components of fatigue can occur via neural pathways, including feedback and feedforward processes. This brief review discusses the influence of feedback and feedforward mechanisms on exercise limitation. In terms of feedback mechanisms, particular attention is given to group III/IV sensory neurons which link limb muscle with the central nervous system. Central corollary discharge, a copy of the neural drive from the brain to the working muscles, provides a signal from the motor system to sensory systems and is considered a feedforward mechanism that might influence fatigue and consequently exercise performance. We highlight findings from studies supporting the existence of a 'critical threshold of peripheral fatigue', a previously proposed hypothesis based on the idea that a negative feedback loop operates to protect the exercising limb muscle from severe threats to homeostasis during whole-body exercise. While the threshold theory remains to be disproven within a given task, it is not generalisable across different exercise modalities. The 'sensory tolerance limit', a more theoretical concept, may address this issue and explain exercise tolerance in more global terms and across exercise modalities. The 'sensory tolerance limit' can be viewed as a negative feedback loop which accounts for the sum of all feedback (locomotor muscles, respiratory muscles, organs, and muscles not directly involved in exercise) and feedforward signals processed within the central nervous system with the purpose of regulating the intensity of exercise to ensure that voluntary activity remains tolerable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.