ArticlePloS one2016
Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The Critical Role of Mental Health Specialists in Organ Transplantation Teams: An ELPAT Position Statement.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- All-cause and cause-specific mortality in people with depression: a large-scale systematic review and meta-analysis of relative risk and aggravating or attenuating factors, including antidepressant treatment.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Emotional affect in heart transplant candidates: a multicenter longitudinal study.Frontiers in psychology · 2025Article
- Depressive symptom as a risk factor for cirrhosis in patients with primary biliary cholangitis: Analysis based on Lasso-logistic regression and decision tree models.Brain and behavior · 2024Article
- Disparities in Liver Transplantation Rates and Outcomes Among Adults with and without Mental Illnesses.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Prevalence of depression and anxiety symptoms by liver disease etiology.Clinical liver disease · 2023Review
- Comorbid psychiatric disorders and long-term survival after liver transplantation in transplant facilities with a psychiatric consultation-liaison team: a multicenter retrospective study.BMC gastroenterology · 2023Article
- Assessment of mental health in patients with chronic liver disease.Clinical liver disease · 2022Review
- COVID-19 Pandemic Stress-Induced Somatization in Transplant Waiting List Patients.Frontiers in psychiatry · 2021Article
- Women who undergo liver transplant have longer length of stay post-transplant compared with men.Liver international : official journal of the International Association for the Study of the Liver · 2020Article
- Article
- Impact of psychosocial comorbidities on clinical outcomes after liver transplantation: Stratification of a high-risk population.World journal of hepatology · 2019Article
- A Behavioral Health Program for Alcohol Use Disorder, Substance Abuse, and Depression in Chronic Liver Disease.Hepatology communications · 2019Article
- The feasibility of a group stress management Liver SMART intervention for patients with end-stage liver disease: A pilot study.Palliative & supportive care · 2019Article
- Depressive symptoms, frailty, and adverse outcomes among kidney transplant recipients.Clinical transplantation · 2018Article
- Review
- Using a natural language processing toolkit to classify electronic health records by psychiatric diagnosis.Health informatics journalArticle
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression after liver transplantation has been associated with decreased survival, but the effects of pre-transplant depression on early and late post-transplant outcomes remain incompletely evaluated. We assessed all patients who had undergone single-organ liver transplantation at a single center over the prior 10 years. A diagnosis of pre-transplant depression, covariates, and the outcomes of interest were extracted from the electronic medical record. Potential covariates included demographics, etiology and severity of liver disease, comorbidities, donor age, graft type, immunosuppression, and ischemic times. In multivariable models adjusting for these factors, we evaluated the effect of pre-transplant depression on transplant length of stay (LOS), discharge disposition (home vs. facility) and long-term survival. Among 1115 transplant recipients with a median follow-up time of 5 years, the average age was 56±11 and MELD was 12±9. Nineteen percent of the study population had a history of pre-transplant depression. Pre-transplant depression was associated with longer LOS (median = 19 vs. 14 days, IRR = 1.25, CI = 1.13,1.39), discharge to a facility (36% vs. 25%, OR 1.70,CI = 1.18,2.45), and decreased survival (HR = 1.54,CI = 1.14,2.08) in this cohort, accounting for other potential confounders. In conclusion, pre-transplant depression was significantly associated with longer transplant length of stay, discharge to a facility, and mortality in this cohort.
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