Evidence map›Paper›PMID 27820804›Full record

ArticleNature chemical biology2017

Genetic engineering: Chemical control for CRISPR editing.

Isaac B Hilton, Charles A Gersbach

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Spatiotemporal control of CRISPR/Cas9 gene editing.Signal transduction and targeted therapy · 2021
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Isaac B HiltonDepartment of Biomedical Engineering and the Center for Genomic &Computational Biology, Duke University, Durham, North Carolina, USA.
Charles A GersbachDepartment of Biomedical Engineering and the Center for Genomic &Computational Biology, Duke University, Durham, North Carolina, USA.

Funding

Engineering Targeted Epigenetic Modifiers for Precise Control of Gene RegulationR01DA036865 · NIDA · DUKE UNIVERSITY · PI CRAWFORD, GREGORY E, GERSBACH, CHARLES A. · 2013 to 2017
$2.6M
NIDA NIH HHS R01 DA036865
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsGene EditingCRISPR-Cas SystemsGenetic EngineeringGenome, Bacterial

Identifiers

PMID27820804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.