Evidence map›Paper›PMID 27820704›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2017

Gastrointestinal hormones and the gut connectome.

Lihua Ye, Rodger A Liddle

Abstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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  20. Gut peptides and the microbiome: focus on ghrelin.Current opinion in endocrinology, diabetes, and obesity · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lihua YeaDepartment of Medicine bDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.
Rodger A Liddle
Duke Medical Center · US

Funding

DUKE TRAINING GRANT IN DIGESTIVE DISEASES AND NUTRITIONT32DK007568 · NIDDK · DUKE UNIVERSITY · PI Katherine Garman, Rodger A. Liddle · 1988 to 2026
$5.6M
Pathogenic Mechanisms of PancreatitisR01DK064213 · NIDDK · DUKE UNIVERSITY · PI LIDDLE, RODGER A. · 2004 to 2017
$4.7M
The role of gut endocrine cells in Parkinson's DiseaseR01DK109368 · NIDDK · DUKE UNIVERSITY · PI LIDDLE, RODGER A. · 2016 to 2019
$1.4M
Receptor Regulation of CCK Cell FunctionR01DK098796 · NIDDK · DUKE UNIVERSITY · PI LIDDLE, RODGER A. · 2013 to 2016
$1.4M
Gut Neuroendocrine Cell Signaling and ObesityI01BX002230 · VA · DURHAM VA MEDICAL CENTER · PI LIDDLE, RODGER A. · 2014 to 2022
–
BLRD VA I01 BX002230NIDDK NIH HHS R01 DK064213NIDDK NIH HHS R01 DK098796NIDDK NIH HHS R01 DK109368NIDDK NIH HHS T32 DK007568
6 · The paper itself

Abstract

purpose of reviewProvision of adequate nutrients by the gut is essential for survival and essential behaviors are linked to the proper ingestion and digestion of food. Recently, a new neural connection has been reported between sensory cells of the gut epithelium and the nervous system that mediates signals from the gut to the brain. RECENT

findingsThis review describes how the gut senses its environment, relays those signals to the brain, and how the brain influences the gut. SUMMARY: This gut-brain connection provides a pathway for how the body handles food.

Indexed as

ConnectomeAnimalsBrainDigestionEatingEnteroendocrine CellsGastrointestinal HormonesGastrointestinal MicrobiomeGastrointestinal TractHumansGastrointestinal Hormones

Identifiers

PMID27820704
PMCPMC5815400
OpenAlexW2548661678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.