Evidence map›Paper›PMID 27819842›Full record

ArticleAlzheimer disease and associated disorders

Low-dose Lithium Treatment for Agitation and Psychosis in Alzheimer Disease and Frontotemporal Dementia: A Case Series.

Davangere P Devanand, Gregory H Pelton, Kristina D'Antonio, Jesse G Strickler, William C Kreisl, James Noble, Karen Marder, Anne Skomorowsky, Edward D Huey

Open access · greenAbstract readCase Reports
In one paragraph

Article in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Trial
  4. Neuropsychiatric symptoms in Alzheimer's disease: Bridging mechanisms, management, and emerging innovations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. New Approaches to the Treatment of Frontotemporal Dementia.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Psychosis in Alzheimer's Disease.Current neurology and neuroscience reports · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Davangere P Devanand*Department of Neurology and Psychiatry †Taub Institute for Research on Alzheimer's Disease and the Aging Brain ‡Sergievsky Center §Division of Geriatric Psychiatry, New York State Psychiatric Institute ∥Columbia University Medical Center, New York, NY.
Gregory H Pelton
Kristina D'Antonio
Jesse G Strickler
William C Kreisl
James Noble
Karen Marder
Anne Skomorowsky
Edward D Huey
Columbia University Irving Medical Center · USNew York State Psychiatric Institute

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
Coenzyme Q10 in Huntingtons DiseaseU01NS052592 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CUDKOWICZ, MERIT E · 2008 to 2013
$7.3M
Treatment of psychosis and agitation in Alzheimers diseaseR01AG047146 · NIA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI DEVANAND, DAVANGERE P · 2014 to 2018
$2.9M
Examination of the earliest symptoms and biomarkers of FTLD MAPT carriersR01NS076837 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COSENTINO, STEPHANIE ANN, HUEY, EDWARD D · 2012 to 2016
$2.5M
Investigation of the dopamine system in frontotemporal dementiaR00NS060766 · NINDS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI HUEY, EDWARD D · 2009 to 2011
$732k
NCRR NIH HHS UL1 RR024156NIA NIH HHS R01 AG047146NINDS NIH HHS R00 NS060766NINDS NIH HHS R01 NS076837NINDS NIH HHS U01 NS052592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAlzheimer DiseaseAntidepressive AgentsFemaleFrontotemporal DementiaHumansLithium CompoundsMalePsychomotor AgitationPsychotic DisordersAntidepressive AgentsLithium Compounds

Identifiers

PMID27819842
PMCPMC5322244
OpenAlexW2547593066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.