Evidence map›Paper›PMID 27819757›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Urethral Pressure Variation: A neglected contributing factor in patients with overactive bladder syndrome?

Kirschner-Hermanns Ruth, Anding Ralf, Gadzhiev Nariman, Goping Ing, Campbell Adele, Huppertz Nadine

Open access · diamondAbstract read
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kirschner-Hermanns RuthDepartament of Neuro-urology, University Hospital Friederich Wilhelms, University Bonn, Germany.
Anding RalfDepartament of Neuro-urology, University Hospital Friederich Wilhelms, University Bonn, Germany.
Gadzhiev NarimanDepartment of Urology, The Federal State Institute of Public Health, The Nikiforov Russian Center of Emergency and Radiation Medicine, Saint-Petersburg, Russian Federation.
Goping IngLaborie, Mississauga, ON, Canada.
Campbell AdeleLaborie, Mississauga, ON, Canada.
Huppertz NadineDepartament of Neuro-urology, University Hospital Friederich Wilhelms, University Bonn, Germany.
University of Bonn · DENikiforov Russian Center of Emergency and Radiation Medicine · RUUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study urethral pressure variations during the whole filling phase among different groups of patients. MATERIAL AND

methodsWe investigated 79 consecutive patients from January 2011 to June 2012. All patients were recruited within our routine practice in our continence clinic and were evaluated with urodynamic exam according to the standards of the International Continence Society (ICS) with an additional continuous measurement of the urethral pressure profile (cUPP) that was done in a supine position. Patients with genital prolapse >grade I, as well as patients with impaired cognitive function or neurogenic disorders were excluded. Bacteriuria at the time of investigation was excluded by urine analysis. Urethral pressure changes higher than 15cmH2O were considered as 'urethral instability'.

resultsFrom 79 investigated patients, 29 were clinically diagnosed with OAB syndrome, 19 with stress urinary incontinence (SUI) and 31 with mixed (OAB and SUI) incontinence. The prevalence of 'urethral instability' as defined in this study was 54.4% (43/79). The mean Δp in patients with OAB (36.5cmH2O) was significantly higher (p<0.05) than in groups with pure stress (14.9cmH2O) and mixed urinary incontinence (19.3cmH2O).

conclusionsEtiology of 'urethral instability' is unknown, but high prevalence among patients with overactive bladder syndrome, especially concomitant with detrusor activity can raise a fair question and direct further diagnostic as well as treatment efforts.

Indexed as

PressureAdultArea Under CurveElectromyographyFemaleFourier AnalysisHumansMiddle AgedReference ValuesRisk FactorsStatistics, NonparametricUrethraUrinary BladderUrinary Bladder, OveractiveUrinary IncontinenceUrodynamicsUrethraUrinary Bladder, OveractiveUrodynamics

Identifiers

PMID27819757
PMCPMC5433367
OpenAlexW2561229979

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.