ArticleEmotion (Washington, D.C.)2017
Error-related brain activity is related to aversive potentiation of the startle response in children, but only the ERN is associated with anxiety disorders.
Article in Emotion (Washington, D.C.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Age-related differences in the error-related negativity and error positivity in children and adolescents are moderated by sample and methodological characteristics: A meta-analysis.Psychophysiology · 2022Pooled it
- Adolescent cognitive control processing is associated with anxiety in young adulthood during the COVID-19 pandemic.Cognitive, affective & behavioral neuroscience · 2025Article
- Emotion Regulation Moderates the Prospective Association between ERN and Anxiety in Early Adolescence: An Age-Specific Moderation of Cognitive Reappraisal but not Expressive Suppression.Research on child and adolescent psychopathology · 2025Article
- Associations between error-related negativity and childhood anxiety risk differ based on socioeconomic status.Developmental psychology · 2023Article
- Cross-sectional and Longitudinal Associations of Anxiety and Irritability With Adolescents' Neural Responses to Cognitive Conflict.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Startle to neutral, not negative stimuli: A neurophysiological correlate of behavioral inhibition in young children.Developmental psychobiology · 2021Article
- The error-related negativity as a neuromarker of risk or resilience in young children.Brain and behavior · 2021Article
- A Diagnostic Biomarker for Pediatric Generalized Anxiety Disorder Using the Error-Related Negativity.Child psychiatry and human development · 2020Article
- The error-related negativity (ERN) moderates the association between interpersonal stress and anxiety symptoms six months later.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020Article
- Developmental trajectory of the late positive potential: Using temporal-spatial PCA to characterize within-subject developmental changes in emotional processing.Psychophysiology · 2020Article
- Impact of pubertal timing and depression on error-related brain activity in anxious youth.Developmental psychobiology · 2019Article
- A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females.Journal of child psychology and psychiatry, and allied disciplines · 2018Article
- Individual differences in combat experiences and error-related brain activity in OEF/OIF/OND veterans.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2018Article
- The Nature of the Relationship between Anxiety and the Error-Related Negativity across Development.Current behavioral neuroscience reports · 2017Article
- A biomarker of anxiety in children and adolescents: A review focusing on the error-related negativity (ERN) and anxiety across development.Developmental cognitive neuroscience · 2017Review
- Impact of anxiety symptoms and problematic alcohol use on error-related brain activity.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017Article
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Abstract
Identifying biomarkers that characterize developmental trajectories leading to anxiety disorders will likely improve early intervention strategies as well as increase our understanding of the etiopathogenesis of these disorders. The error-related negativity (ERN), an event-related potential that occurs during error commission, is increased in anxious adults and children-and has been shown to predict the onset of anxiety disorders across childhood. The ERN has therefore been suggested as a biomarker of anxiety. However, it remains unclear what specific processes a potentiated ERN may reflect. We have recently proposed that the ERN may reflect trait-like differences in threat sensitivity; however, very few studies have examined the ERN in relation to other indices of this construct. In the current study, the authors measured the ERN, as well as affective modulation of the startle reflex, in a large sample (N = 155) of children. Children characterized by a large ERN also exhibited greater potentiation of the startle response in the context of unpleasant images, but not in the context of neutral or pleasant images. In addition, the ERN, but not startle response, related to child anxiety disorder status. These results suggest a relationship between error-related brain activity and aversive potentiation of the startle reflex during picture viewing-consistent with the notion that both measures may reflect individual differences in threat sensitivity. However, results suggest the ERN may be a superior biomarker of anxiety in children. (PsycINFO Database Record
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