Evidence map›Paper›PMID 27819339›Full record

ArticleScientific reports2016

Recombinant spider silk from aqueous solutions via a bio-inspired microfluidic chip.

Qingfa Peng, Yaopeng Zhang, Li Lu, Huili Shao, Kankan Qin, Xuechao Hu, Xiaoxia Xia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Article
  3. Highly-Strong and Highly-Tough Alginate Fibers with Photo-Modulating Mechanical Properties.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Complexity of Spider Dragline Silk.Biomacromolecules · 2022
    Review
  15. Spider Silk-Inspired Artificial Fibers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Silkworm and spider silk electrospinning: a review.Environmental chemistry letters · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qingfa PengState Key Laboratory for Modification of Chemical Fibres and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.
Yaopeng ZhangState Key Laboratory for Modification of Chemical Fibres and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.
Li LuState Key Laboratory for Modification of Chemical Fibres and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.
Huili ShaoState Key Laboratory for Modification of Chemical Fibres and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.
Kankan QinSchool of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Xuechao HuState Key Laboratory for Modification of Chemical Fibres and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.
Xiaoxia XiaSchool of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Donghua University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spiders achieve superior silk fibres by controlling the molecular assembly of silk proteins and the hierarchical structure of fibres. However, current wet-spinning process for recombinant spidroins oversimplifies the natural spinning process. Here, water-soluble recombinant spider dragline silk protein (with a low molecular weight of 47 kDa) was adopted to prepare aqueous spinning dope. Artificial spider silks were spun via microfluidic wet-spinning, using a continuous post-spin drawing process (WS-PSD). By mimicking the natural spinning apparatus, shearing and elongational sections were integrated in the microfluidic spinning chip to induce assembly, orientation of spidroins, and fibril structure formation. The additional post-spin drawing process following the wet-spinning section partially mimics the spinning process of natural spider silk and substantially contributes to the compact aggregation of microfibrils. Subsequent post-stretching further improves the hierarchical structure of the fibres, including the crystalline structure, orientation, and fibril melting. The tensile strength and elongation of post-treated fibres reached up to 510 MPa and 15%, respectively.

Indexed as

Amino Acid SequenceAnimalsFibroinsMicrofluidicsMicroscopy, Electron, ScanningRecombinant ProteinsSilkSpectrometry, X-Ray EmissionSpidersTensile StrengthWaterFibroinsRecombinant ProteinsSilkWater

Identifiers

PMID27819339
PMCPMC5098227
OpenAlexW2551193344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.