Trial reportScientific reports2016
Epidemiology of hepatitis B virus infection: results from a community-based study of 0.15 million residents in South China.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hepatitis B infection in the general population of China: a systematic review and meta-analysis.BMC infectious diseases · 2019Pooled it
- A systematic review of hepatitis B screening economic evaluations in low- and middle-income countries.BMC public health · 2018Pooled it
- Trends in clinical intervention practice for preventing mother-to-child transmission of hepatitis B virus in Guangdong Province, 2021-2023.Human vaccines & immunotherapeutics · 2026Article
- Article
- Feasibility of eliminating adult hepatitis B in Guangdong by 2030: A modeling study.Infectious Disease Modelling · 2026Article
- Clinical correlation and survival analysis of hepatitis B virus infection in oral squamous cell carcinoma: a retrospective study of 1373 patients.BMC cancer · 2025Article
- Effectiveness of catch-up vaccination from 2009 to 2011 on incidence of hepatitis B in Guangzhou, China: a time series analysis.BMC public health · 2025Article
- The impact of donor hepatitis B virus infection on transplant outcomes in deceased donor kidney transplantation recipients.Kidney research and clinical practice · 2025Article
- Impact and Cost-Effectiveness of Biomedical Interventions on Adult Hepatitis B Elimination in China: A Mathematical Modelling Study.Journal of epidemiology and global health · 2023Article
- Epidemiology of hepatitis B virus infection among preconception couples in South China: a cross-sectional study.BMJ open · 2023Article
- High HBV-DNA serum levels are associated with type 2 diabetes in adults with positive HBsAg: An observational study.Frontiers in endocrinology · 2023Observational
- Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study.BMC infectious diseases · 2022Article
- Conventional and genetic risk factors for chronic Hepatitis B virus infection in a community-based study of 0.5 million Chinese adults.Scientific reports · 2022Article
- High-Frequency Notable HBV Mutations Identified in Blood Donors With Occult Hepatitis B Infection From Heyuan City of Southern China.Frontiers in immunology · 2022Article
- Effect of a Community-Based Hepatitis B Virus Infection Detection Combined with Vaccination Program in China.Vaccines · 2021Article
- Diagnosis experiences from 50 hepatitis B patients in Chongqing, China: a qualitative study.BMC public health · 2021Article
- Epidemiologic profile of viral hepatitis B and C in North of Iran: results from PERSIAN Guilan Cohort Study (PGCS).BMC research notes · 2021Article
- Prevalence of HBsAg among reproductive age couples in Chongqing: A population-based, cross-sectional study.PloS one · 2021Article
- An expert review on the use of tenofovir alafenamide for the treatment of chronic hepatitis B virus infection in Asia.Journal of gastroenterology · 2020Review
- Systematic analysis on multiple Gene Expression Omnibus data sets reveals fierce immune response in hepatitis B virus-related acute liver failure.Journal of cellular and molecular medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limited information is available about the current epidemic status of hepatitis B virus (HBV) in Guangdong province in South China, where hepatitis B is endemic. We sought to provide an up-to-date assessment of hepatitis B prevalence in a large population through a community-based study. A total of 169,211 local residents were recruited using the stratified cluster random sampling method from 2014 to 2015, and each participant's information was collected using an interviewer-administered questionnaire. Accordingly, the prevalence of hepatitis B surface antigen (HBsAg) in the total population was 8.76%. HBsAg prevalence was lowest (0.29%) among children aged 0-12 years and highest (12.71%) among those aged 23-59 years. Moreover, the prevalence (8.82%) in males approximately equalled that (8.65%) in females (P > 0.05). Overall, vaccination was effective in preventing HBV infection, regardless of age. Among adults aged 23-59 years, male sex tended to keep the HBsAg persistence. However, reduced persistence for participants with occasional physical exercise and drinking was observed. For participants older than 59 years, a history of prior surgery placed people at high risk for infection. Although Guangdong has successfully decreased the HBsAg prevalence among children, it is urgent to expand vaccination to adults, and employ interventions to reduce the infection risk.
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