Evidence map›Paper›PMID 27819299›Full record

ArticleNature communications2016

Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission.

Himanish Ghosh, Luca Auguadri, Sereina Battaglia, Zahra Simone Thirouin, Khaled Zemoura, Simon Messner, Mario A Acuña, Hendrik Wildner, Gonzalo E Yévenes, Andrea Dieter and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Knocking Down PIAS3 Reduces HCell biochemistry and biophysics · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Generational synaptic functions of GABAJournal of biomedical science · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Himanish GhoshInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Luca AuguadriInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Sereina BattagliaInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Zahra Simone ThirouinInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Khaled ZemouraInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Simon MessnerDepartment of Molecular Mechanisms of Disease, University of Zurich, CH 8057 Zurich, Switzerland.
Mario A AcuñaInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Hendrik WildnerInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Gonzalo E YévenesInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Andrea DieterInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Hiroshi KawasakiDepartment of Molecular and Systems Neurobiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
Michael O HottigerDepartment of Molecular Mechanisms of Disease, University of Zurich, CH 8057 Zurich, Switzerland.
Hanns Ulrich ZeilhoferInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.
Jean-Marc FritschyInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.ORCID 0000-0002-8552-3702
Shiva K TyagarajanInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland.ORCID 0000-0003-0074-1805
ZHAW Zurich University of Applied Sciences · CHUniversity of Zurich · CHThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GABA

Indexed as

AcetylationAnimalsCA1 Region, HippocampalCarrier ProteinsFemaleFlavonesGABAergic NeuronsHEK293 CellsHumansMaleMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutModels, AnimalNeocortex2',3',4'-trihydroxyflavoneCarrier ProteinsFlavonesGabra2 protein, mousegephyrinMembrane ProteinsReceptors, GABA-A

Identifiers

PMID27819299
PMCPMC5103071
OpenAlexW2553797215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.