Evidence map›Paper›PMID 27819065›Full record

ArticleACS omega2016

Characterization of Mg

Justin A Lemkul, Sirish Kaushik Lakkaraju, Alexander D MacKerell

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Influence of MgACS omega · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Contributions and competition of MgRNA (New York, N.Y.) · 2020
    Article
  8. Article
  9. MgBiophysical journal · 2020
    Article
  10. Article
  11. Ions Everywhere? MgBiophysical journal · 2020
    Article
  12. Theory and simulations for RNA folding in mixtures of monovalent and divalent cations.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Article
  15. Nucleobase carbonyl groups are poor MgRNA (New York, N.Y.) · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Justin A LemkulDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore , 20 Penn Street, HSF II, Room 633, Baltimore, Maryland 21201, United States.
Sirish Kaushik LakkarajuDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore , 20 Penn Street, HSF II, Room 633, Baltimore, Maryland 21201, United States.
Alexander D MacKerellDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore , 20 Penn Street, HSF II, Room 633, Baltimore, Maryland 21201, United States.
University of Maryland, Baltimore · US

Funding

Oligonucleotide Conformational HeterogeneityR01GM051501 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D · 2003 to 2018
$3.6M
Carbohydrate force fields for structure, dynamics and molecular recognitionR01GM070855 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D · 2005 to 2018
$3.5M
Exploring RNA Folding and Dynamics Using a Polarizable Force FieldF32GM109632 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI LEMKUL, JUSTIN ALAN · 2014 to 2016
$164k
HALOGEN FREE ENERGY DATABASE FOR RATIONAL DRUG DESIGNR29GM051501 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D. · 1996 to 2000
$108k
NIGMS NIH HHS F32 GM109632NIGMS NIH HHS R01 GM051501NIGMS NIH HHS R01 GM070855NIGMS NIH HHS R29 GM051501
6 · The paper itself

Abstract

Binding of metal ions is an important factor governing the folding and dynamics of RNA. Shielding of charges in the polyanionic backbone allows RNA to adopt a diverse range of folded structures that give rise to their many functions within the cell. Some RNA sequences fold only in the presence of Mg

Identifiers

PMID27819065
PMCPMC5088455
OpenAlexW2543023894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.