ArticleScience advances2016
Constructing 3D heterogeneous hydrogels from electrically manipulated prepolymer droplets and crosslinked microgels.
Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Digital Microfluidic Multiplex RT-qPCR for SARS-CoV-2 Detection and Variants Discrimination.Micromachines · 2023Article
- Phase-separation facilitated one-step fabrication of multiscale heterogeneous two-aqueous-phase gel.Nature communications · 2023Article
- Microfluidic Formulation of Topological Hydrogels for Microtissue Engineering.Chemical reviews · 2022Review
- Electro-Microfluidic Assembly Platform for Manipulating Colloidal Structures inside Water-in-Oil Emulsion Droplets.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Reversible Design of Dynamic Assemblies at Small Scales.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2021Article
- Capacitance Effects of a Hydrophobic-Coated Ion Gel Dielectric on AC Electrowetting.Micromachines · 2021Article
- Designing Microgels for Cell Culture and Controlled Assembly of Tissue Microenvironments.Advanced functional materials · 2020Article
- Cell invasion in digital microfluidic microgel systems.Science advances · 2020Article
- Hydrogel 3D printing with the capacitor edge effect.Science advances · 2019Article
- Determination of Aqueous Two-Phase System Binodals and Tie-Lines by Electrowetting-on-Dielectric Droplet Manipulation.Chembiochem : a European journal of chemical biology · 2019Article
- From Neuronal Differentiation of iPSCs to 3D Neuro-Organoids: Modelling and Therapy of Neurodegenerative Diseases.International journal of molecular sciences · 2018Review
- Biofabrication strategies for 3D in vitro models and regenerative medicine.Nature reviews. Materials · 2018Article
- Creating tissue on chip constructs in microtitre plates for drug discovery.RSC advances · 2018Article
- The rise of three-dimensional human brain cultures.Nature · 2018Review
- Integrating Immunology and Microfluidics for Single Immune Cell Analysis.Frontiers in immunology · 2018Review
- Review on optofluidic microreactors for artificial photosynthesis.Beilstein journal of nanotechnology · 2018Review
- Controllable Swarming and Assembly of Micro/Nanomachines.Micromachines · 2017Review
- Colloidal shuttles for programmable cargo transport.Nature communications · 2017Article
- Combining ATRP and FRP Gels: Soft Gluing of Polymeric Materials for the Fabrication of Stackable Gels.Polymers · 2017Article
- OpenDrop: An Integrated Do-It-Yourself Platform for Personal Use of Biochips.Bioengineering (Basel, Switzerland) · 2017Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Formation of multifunctional, heterogeneous, and encoded hydrogel building blocks, or microgels, by crosslinking and assembly of microgels are two essential steps in establishing hierarchical, complicated, and three-dimensional (3D) hydrogel architectures that recapitulate natural and biological structures or originate new materials by design. However, for the variety of the hydrogel materials crosslinked differently and for the varied scales of microgels and architectures, the formation and assembly processes are usually performed separately, which increases the manufacturing complexity of designed hydrogel materials. We show the construction of hydrogel architectures through programmable formation and assembly on an electromicrofluidic platform, adopting two reciprocal electric manipulations (electrowetting and dielectrophoresis) to manipulate varied objects (i) in multiple phases, including prepolymer liquid droplets and crosslinked microgels, (ii) on a wide range of scales from micrometer functional particles or cells to millimeter-assembled hydrogel architectures, and (iii) with diverse properties, such as conductive and dielectric droplets that are photocrosslinkable, chemically crosslinkable, or thermally crosslinkable. Prepolymer droplets, particles, and dissolved molecules are electrically addressable to adjust the properties of the microgel building blocks in liquid phase that subsequently undergo crosslinking and assembly in a flexible sequence to accomplish heterogeneous and seamless hydrogel architectures. We expect the electromicrofluidic platform to become a general technique to obtain 3D complex architectures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.