ArticleLight, science & applications2016
Optical disassembly of cellular clusters by tunable 'tug-of-war' tweezers.
Article in Light, science & applications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 60 citations in OpenAlex.
- Optical trapping stability of different irregularly shaped microplastic particles.Scientific reports · 2025Article
- Laser-Induced Photothermal Pulling of Dyed Droplets on a Superhydrophobic Surface.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Photon-efficient optical tweezers via wavefront shaping.Science advances · 2024Article
- Shining Light in Mechanobiology: Optical Tweezers, Scissors, and Beyond.ACS photonics · 2024Review
- Biofilm formation and manipulation with optical tweezers.Biomedical optics express · 2024Article
- Optical skipping rope induced transverse OAM for particle orbital motion parallel to the optical axis.Nanophotonics (Berlin, Germany) · 2023Article
- Looking at Biomolecular Interactions through the Lens of Correlated Fluorescence Microscopy and Optical Tweezers.International journal of molecular sciences · 2023Review
- Hysteresis and balance of backaction force on dielectric particles photothermally mediated by photonic nanojet.Nanophotonics (Berlin, Germany) · 2022Article
- Positioning Accuracy in Holographic Optical Traps.Micromachines · 2021Article
- Hysteresis Modelling and Feedforward Control of Piezoelectric Actuator Based on Simplified Interval Type-2 Fuzzy System.Sensors (Basel, Switzerland) · 2020Article
- Optical Tweezers Exploring Neuroscience.Frontiers in bioengineering and biotechnology · 2020Review
- Manipulating rod-shaped bacteria with optical tweezers.Scientific reports · 2019Article
- Optical Tweezers: Phototoxicity and Thermal Stress in Cells and Biomolecules.Micromachines · 2019Review
- Optical force-induced nonlinearity and self-guiding of light in human red blood cell suspensions.Light, science & applications · 2019Article
- Piezoelectric Actuated Phase Shifter Based on External Laser Interferometer: Design, Control and Experimental Validation.Sensors (Basel, Switzerland) · 2017Article
- Extending calibration-free force measurements to optically-trapped rod-shaped samples.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
Bacterial biofilms underlie many persistent infections, posing major hurdles in antibiotic treatment. Here we design and demonstrate 'tug-of-war' optical tweezers that can facilitate the assessment of cell-cell adhesion-a key contributing factor to biofilm development, thanks to the combined actions of optical scattering and gradient forces. With a customized optical landscape distinct from that of conventional tweezers, not only can such 'tug-of-war' tweezers stably trap and stretch a rod-shaped bacterium in the observing plane, but, more importantly, they can also impose a tunable lateral force that pulls apart cellular clusters without any tethering or mechanical movement. As a proof of principle, we examined a
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.