ArticleThe Journal of pediatrics2017
Racial Differences in Aortic Stiffness in Children.
Article in The Journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Exercise effects on arterial stiffness and heart health in children with excess weight: The SMART RCT.International journal of obesity (2005) · 2020Trial
- Effect of vitamin D3 supplementation on vascular and metabolic health of vitamin D-deficient overweight and obese children: a randomized clinical trial.The American journal of clinical nutrition · 2020Trial
- The costs and benefits of striving: Subclinical cardiovascular disease, depression, and hostility as children navigate adversity.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Associations of noninvasive measures of adiposity with aortic stiffness and microvascular function: The Jackson Heart Study.American journal of preventive cardiology · 2026Article
- Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships.Reviews in cardiovascular medicine · 2025Review
- Acute inflammation elicits decreased blood pressure but similar arterial stiffness in young African American adults.Experimental physiology · 2024Article
- Race, cortisol, and subclinical cardiovascular disease in 9- to 11-year-old children.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023Article
- Physical activity is associated with lower pulsatile stress but not carotid stiffness in children.Journal of human hypertension · 2022Article
- Associations between estimated and measured carotid-femoral pulse wave velocity in older Black and White adults: the atherosclerosis risk in communities (ARIC) study.The journal of cardiovascular aging · 2022Article
- Social Determinants of Cardiovascular Health in African American Children With CKD: An Analysis of the Chronic Kidney Disease in Children (CKiD) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021Article
- Racial differences of early vascular aging in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2021Review
- Aortic Stiffness: Epidemiology, Risk Factors, and Relevant Biomarkers.Frontiers in cardiovascular medicine · 2021Review
- Cross-Talk Between Large Artery Stiffness and Retinal Microvasculature in Children: The ExAMIN Youth SA Study.Frontiers in pediatrics · 2021Article
- Race Differences in the Effect of Subjective Social Status on Hostility and Depressive Symptoms Among 9- to 11-Year-Old Children.Journal of racial and ethnic health disparities · 2020Article
- Clinical Associations of Vascular Stiffness, Microvascular Dysfunction, and Prevalent Cardiovascular Disease in a Black Cohort: The Jackson Heart Study.Journal of the American Heart Association · 2020Article
- Article
- Racial Differences in Left Ventricular Mass and Wave Reflection Intensity in Children.Frontiers in pediatrics · 2020Article
- Racial differences in myocardial deformation in obese children: Significance of inflammatory state.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2019Article
- Students of color show health advantages when they attend schools that emphasize the value of diversity.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Variability in the spatial density of vacant properties contributes to background lead (Pb) exposure in children.Environmental research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate racial differences in central blood pressure and vascular structure/function as subclinical markers of atherosclerotic cardiovascular disease in children. STUDY
designThis cross-sectional study recruited 54 African American children (18 female, 36 male; age 10.5 ± 0.9 years) and 54 white children (27 female, 26 male; age 10.8 ± 0.9 years) from the Syracuse City community as part of the Environmental Exposures and Child Health Outcomes study. Participants underwent blood lipid and vascular testing on 2 separate days. Carotid artery intima-media thickness and aortic stiffness were measured by ultrasonography and carotid-femoral pulse wave velocity, respectively. Blood pressure was assessed at the brachial artery and estimated in the carotid artery using applanation tonometry.
resultsAfrican American children had significantly higher pulse wave velocity (4.8 ± 0.8 m/s) compared with white children (4.2 ± 0.7 m/s; P < .05), which remained significant after adjustment for confounding variables including socioeconomic status. African American children had significantly higher intima-media thickness (African American 0.41 ± 0.06, white 0.39 ± 0.05 mm), and carotid systolic blood pressure (African American 106 ± 11, white 102 ± 8 mm Hg; P < .05) compared with white children, although these racial differences were no longer present after covariate adjustments for height.
conclusionsRacial differences in aortic stiffness are present in childhood. Our findings suggest that racial differences in subclinical cardiovascular disease occur earlier than previously recognized.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.