Evidence map›Paper›PMID 27817181›Full record

ReviewStem cell reviews and reports2017

Reprogramming Enhancers in Somatic Cell Nuclear Transfer, iPSC Technology, and Direct Conversion.

Daekee Kwon, Minjun Ji, Seunghee Lee, Kwang Won Seo, Kyung-Sun Kang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. SEC Mediates mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Potential application of cell reprogramming techniques for cancer research.Cellular and molecular life sciences : CMLS · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daekee KwonStem Cells and Regenerative Bioengineering Institute in Kangstem Biotech, Biomedical Science Building, #81 Seoul National University, Seoul, 08826, South Korea.
Minjun JiStem Cells and Regenerative Bioengineering Institute in Kangstem Biotech, Biomedical Science Building, #81 Seoul National University, Seoul, 08826, South Korea.
Seunghee LeeStem Cells and Regenerative Bioengineering Institute in Kangstem Biotech, Biomedical Science Building, #81 Seoul National University, Seoul, 08826, South Korea.
Kwang Won SeoStem Cells and Regenerative Bioengineering Institute in Kangstem Biotech, Biomedical Science Building, #81 Seoul National University, Seoul, 08826, South Korea. kwseo@kangstem.com.
Kyung-Sun KangStem Cells and Regenerative Bioengineering Institute in Kangstem Biotech, Biomedical Science Building, #81 Seoul National University, Seoul, 08826, South Korea. kangpub@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct conversion of cell fate is a core technology for future regenerative medicine. However, the low reprogramming efficiency and low reproducibility are the largest obstacles blocking translational research of direct conversion technology. This review lists the major reprogramming enhancers verified in the representative reprogramming technologies of somatic cell nuclear transfer, induced pluripotent stem cell technology, and direct conversion, and categorizes them according to their functions. Ultimately, we strive to provide a practical plan to overcome the low reprogramming efficiency and low reproducibility of direct conversion.

Indexed as

Cell DifferentiationCellular ReprogrammingNuclear Transfer TechniquesAnimalsCell Culture TechniquesHumansInduced Pluripotent Stem CellsRegenerative MedicineReproducibility of ResultsDirect conversionInduced pluripotent stem cellsReprogrammingReprogramming efficiencyReprogramming enhancerSomatic cell nuclear transfer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.