Evidence map›Paper›PMID 27817037›Full record

Observational studyJournal of assisted reproduction and genetics2017

Effect of body mass index on the outcomes of controlled ovarian hyperstimulation in Chinese women with polycystic ovary syndrome: a multicenter, prospective, observational study.

Yan Sheng, Guangxiu Lu, Jiayin Liu, Xiaoyan Liang, Yanping Ma, Xuehong Zhang, Songying Zhang, Yingpu Sun, Yun Sun, Wenfeng Chen and 2 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  18. Active unicameral bone cysts: control firstly, cure secondly.Journal of orthopaedic surgery and research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Yan ShengCenter for Reproductive Medicine, Shandong University, Jinan, China.
Guangxiu LuReproductive & Genetic Hospital CITIC-Xiangya, Changsha, China.
Jiayin LiuJiangsu Province Hospital, Nanjing, China.
Xiaoyan LiangThe Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yanping MaThe First People's Hospital of Yunnan Province, Kunming, China.
Xuehong ZhangThe First Hospital of Lanzhou University, Lanzhou, China.
Songying ZhangSir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yingpu SunThe First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yun SunRenji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wenfeng ChenMerck Serono Co., Ltd, Beijing, China.
Wenhui FangMerck Serono Co., Ltd, Beijing, China.
Zijiang ChenCenter for Reproductive Medicine, Shandong University, Jinan, China. chenzijiang@hotmail.com.
First Affiliated Hospital of Zhengzhou University · CNShandong University · CNFirst Hospital of Lanzhou University · CNFirst People's Hospital of Yunnan Province · CNJiangsu Province Hospital · CNReproductive & Genetic Hospital CITIC-Xiangya · CNSixth Affiliated Hospital of Sun Yat-sen University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of the present study is to explore the influence of body mass index (BMI) on outcomes of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) techniques in Chinese women with polycystic ovary syndrome (PCOS).

methodsThis was a multicenter, prospective, observational study that enrolled 800 subjects with PCOS from nine hospitals in China. Patients were categorized according to BMI categories: underweight, <18.5 kg/m

resultsAmong the 774 subjects, 27.3 % were overweight and 8.1 % were obese. The rFSH dose used differed significantly among BMI categories (P < 0.001). The implantation rate was lower in obese subjects than that in normal-weight subjects (25.3 vs 45.7 %). Clinical pregnancy rate per transfer differed among BMI categories (P = 0.033), but there was no difference for biochemical (P = 0.327) and ongoing (P = 0.084) pregnancy rates. The miscarriage rate was similar among BMI categories.

conclusionsMore than one third of Chinese women with PCOS undergoing IVF/ICSI are overweight or obese. Elevated BMI is associated with reduced clinical pregnancy rate but similar ongoing pregnancy rates, suggesting that BMI has little impact on IVF outcomes.

Indexed as

Body Mass IndexAbortion, SpontaneousAdultAsian PeopleChinaEmbryo TransferFemaleFertilization in VitroHumansObesityOvarian Hyperstimulation SyndromeOverweightOvulation InductionPolycystic Ovary SyndromePregnancyPregnancy RateBody mass indexIntracytoplasmic sperm injectionsIn vitro fertilizationPolycystic ovary syndromePregnancy rate

Identifiers

PMID27817037
PMCPMC5330982
OpenAlexW2546460045

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.