Observational studyAge and ageing2017
Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of a susceptibility score based on factors identified externally in pooled data for use at entry to the acute care pathway.
Observational study in Age and ageing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Risk of bias in prognostic models of hospital-induced delirium for medical-surgical units: A systematic review.PloS one · 2023Pooled it
- Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.The Cochrane database of systematic reviews · 2021Pooled it
- Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients.The Cochrane database of systematic reviews · 2021Pooled it
- Pooled it
- Delirium prevalence, diagnostic uncertainty and outcomes in ORCHARD-EPR: validation against prospective reference cohorts.Age and ageing · 2025Article
- Article
- Boosting Delirium Identification Accuracy With Sentiment-Based Natural Language Processing: Mixed Methods Study.JMIR medical informatics · 2022Article
- Delirium prediction in the ICU: designing a screening tool for preventive interventions.JAMIA open · 2022Article
- Head-to-head comparison of 14 prediction models for postoperative delirium in elderly non-ICU patients: an external validation study.BMJ open · 2022Article
- Opioid and benzodiazepine use in the emergency department and the recognition of delirium within the first 24 hours of hospitalization.Journal of psychosomatic research · 2022Article
- Utility of white matter disease and atrophy on routinely acquired brain imaging for prediction of long-term delirium risk: population-based cohort study.Age and ageing · 2022Article
- Association between the reactivity of local cerebral oxygen saturation after hypo-to-hypercapnic tests and delirium after abdominal surgery in older adults: A prospective study.Frontiers in psychiatry · 2022Article
- Development and validation of a delirium risk assessment tool in older patients admitted to the Emergency Department Observation Unit.Aging clinical and experimental research · 2021Article
- Impact of a system-wide multicomponent intervention on administrative diagnostic coding for delirium and other cognitive frailty syndromes: observational prospective study.Clinical medicine (London, England) · 2020Article
- Risk factors associated with postoperative intensive care unit delirium in patients undergoing invasive mechanical ventilation following acute exacerbation of chronic obstructive pulmonary disease.The Journal of international medical research · 2020Article
- Routine screening in the general hospital: what happens after discharge to those identified as at risk of dementia?Clinical medicine (London, England) · 2017Article
- Early geriatric consultation increases adherence to TQIP Geriatric Trauma Management Guidelines.The Journal of surgical research · 2017Article
- Occurrence and predictors of delirium in critically ill older patients: a prospective cohort study.Porto biomedical journalArticle
- Underestimation of Cognitive Impairment in Older Inpatients by the Abbreviated Mental Test Score versus the Montreal Cognitive Assessment: Cross-Sectional Observational Study.Dementia and geriatric cognitive disorders extraArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Background: recognition of prevalent delirium and prediction of incident delirium may be difficult at first assessment. We therefore aimed to validate a pragmatic delirium susceptibility (for any, prevalent and incident delirium) score for use in front-line clinical practice in a consecutive cohort of older acute medicine patients. Methods: consecutive patients aged ≥65 years over two 8-week periods (2010-12) were screened prospectively for delirium using the Confusion Assessment Method (CAM), and delirium was diagnosed using the DSM IV criteria. The delirium susceptibility score was the sum of weighted risk factors derived using pooled data from UK-NICE guidelines: age >80 = 2, cognitive impairment (cognitive score below cut-off/dementia) = 2, severe illness (systemic inflammatory response syndrome) = 1, infection = 1, visual impairment = 1. Score reliability was determined by the area under the receiver operating curve (AUC). Results: among 308 consecutive patients aged ≥65 years (mean age/SD = 81/8 years, 164 (54%) female), AUC was 0.78 (95% CI 0.71-0.84) for any delirium; 0.71 (0.64-0.79), for prevalent delirium; 0.81 (0.70-0.92), for incident delirium; odds ratios (ORs) for risk score 5-7 versus <2 were 17.9 (5.4-60.0), P < 0.0001 for any delirium, 8.1 (2.2-29.7), P = 0.002 for prevalent delirium, and 25.0 (3.0-208.9) P = 0.003 for incident delirium, with corresponding relative risks of 5.4, 4.7 and 13. Higher risk scores were associated with frailty markers, increased care needs and poor outcomes. Conclusions: the externally derived delirium susceptibility score reliably identified prevalent and incident delirium using clinical data routinely available at initial patient assessment and might therefore aid recognition of vulnerability in acute medical admissions early in the acute care pathway.
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