Evidence map›Paper›PMID 27816663›Full record

ReviewAddictive behaviors2017

Impact of quitting smoking and smoking cessation treatment on substance use outcomes: An updated and narrative review.

Karma McKelvey, Johannes Thrul, Danielle Ramo

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Addictive behaviors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03551704 nacompletednot on this mapstarted 2018, after this paper: background citation

Smoking Cessation Treatment for Substance Use Dependents

TypeinterventionalSponsorUniversity of OviedoRan2018 to 2022Enrolled120ConditionsTobacco Use DisorderArmsCBT + EFT, CBT + EFT + CM
NCT04647097 narecruitingnot on this mapstarted 2022, after this paper: background citation

Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study

TypeinterventionalSponsorUniversity of PecsRan2022 to 2028Enrolled364ConditionsAcute Pancreatitis, Recurrent Acute PancreatitisArmsStandard intervention only, Standard intervention plus repeated intervention
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 131 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Smoking in Substance Use Disorder Patients: Prevalence, Comorbidities, Impulsivity, and Patterns of Readiness to Change.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karma McKelveyCenter for Tobacco Control Research and Education, University of California San Francisco, 530 Parnassus Avenue, Suite 366, San Francisco, CA 94143, USA. Electronic address: Karma.McKelvey@ucsf.edu.
Johannes ThrulCenter for Tobacco Control Research and Education, University of California San Francisco, 530 Parnassus Avenue, Suite 366, San Francisco, CA 94143, USA.
Danielle RamoCenter for Tobacco Control Research and Education, University of California San Francisco, 530 Parnassus Avenue, Suite 366, San Francisco, CA 94143, USA; Department of Psychiatry and Weill Institute for Neurosciences, University of California San Francisco, 401 Parnassus Avenue, Box TRC 0984, San Francisco, CA 94143, USA.
University of California, San Francisco · US

Funding

Postdoctoral training in tobacco controlR25CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2006 to 2015
$5.4M
Postdoctoral training in tobacco controlT32CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LING, PAMELA MAY · 2016 to 2020
$2.6M
Social Media Intervention for Young Adult SmokersK23DA032578 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RAMO, DANIELLE E · 2012 to 2016
$927k
NCI NIH HHS R25 CA113710NCI NIH HHS T32 CA113710NIDA NIH HHS K23 DA032578
6 · The paper itself

Abstract

backgroundHistorically, smoking cessation was thought to negatively impact substance use outcomes among smokers who use other substances. We sought to synthesize recent reports on this association.

methodsGoogle Scholar, PubMed, and Cinahl were searched for studies published from 2006 to March 29, 2016 that reported impact of smoking cessation treatment or quitting smoking on substance use or substance use disorder treatment outcomes in the general population and among those in substance abuse treatment. Studies were grouped by reported impact as follows: "positive" (i.e. improved), "null" (i.e. no change), or "negative" (i.e. worsened).

resultsTwenty-four studies were included. Eighteen reported the impact of quitting smoking and six reported the impact of smoking cessation treatment intervention, independent of quitting, on substance use outcomes. Eleven studies (46%) reported solely positive impact; four (17%) reported solely null impact; eight (33%) reported mixed positive and null impact by analysis (combined and subgroup, n=1); substance (n=4); length of follow-up (n=2); and comparison group (n=1). One study (4%) reported mixed negative and null impact by ethnic group. No studies reported increased substance use.

conclusionSmoking cessation does not appear to have a negative effect, and often has a positive effect on substance use outcomes. Smoking cessation advice should be offered, without hesitation, to smokers who report substance use and those in treatment for substance use disorder.

Indexed as

Smoking CessationHumansSubstance-Related DisordersTobacco SmokingSmoking cessationSmoking cessation treatmentSubstance useSubstance use disorderSubstance use treatment

Identifiers

PMID27816663
PMCPMC5140700
OpenAlexW2541231541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.