ArticleJournal of affective disorders2017
An in-depth look into PTSD-depression comorbidity: A longitudinal study of chronically-exposed Detroit residents.
Article in Journal of affective disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Pooled it
- Trauma-focused guided self-help interventions for posttraumatic stress disorder: A meta-analysis of randomized controlled trials.Depression and anxiety · 2022Pooled it
- Applying network analysis to psychological comorbidity and health behavior: Depression, PTSD, and sexual risk in sexual minority men with trauma histories.Journal of consulting and clinical psychology · 2017Trial
- The Effects of Boko Haram Terrorism on Adolescents' and Young Adults' Psychosocial Adjustment in the Northeast of Nigeria.Transcultural psychiatry · 2026Article
- Investigating PTSD, mental disorders, and suicide through self-comparison: a self-controlled case series study over two decades.Translational psychiatry · 2026Article
- Network structure analysis of post-traumatic stress and depressive symptoms among college students: identification of central and bridge symptoms.Frontiers in psychiatry · 2026Article
- Cognitive appraisals, cognitive avoidance and rumination as shared vulnerabilities for PTSD and depression in trauma-exposed adolescents.European journal of psychotraumatology · 2025Article
- Assessing Perinatal Psychiatric Morbidity: Implications for Maternal Mental Health Care in Italy.Clinical psychology in Europe · 2025Article
- A model for secondary traumatic stress following workplace exposure to traumatic material in analytical staff.Communications psychology · 2024Review
- Dynamic networks of complex posttraumatic stress disorder and depression among college students with childhood trauma: insights from cross-sectional and cross-lagged panel network analysis.European journal of psychotraumatology · 2024Article
- Identifying post-traumatic stress symptom typologies in clinical and non-clinical healthcare staff: a latent profile analysis.European journal of psychotraumatology · 2024Article
- Comorbidity Patterns of Posttraumatic Stress Disorder and Depression Symptoms: Cross-Validation in Two Postearthquake Child and Adolescent Samples.Depression and anxiety · 2023Article
- The effect of pre-pandemic PTSD and depression symptoms on mental distress among older adults during COVID-19.Journal of psychiatric research · 2022Article
- Mindful nonreactivity moderates the relationship between posttraumatic stress disorder and depression.Journal of loss & trauma · 2022Article
- A cluster analytic approach to examining the role of cortisol in the development of post-traumatic stress and dysphoria in adult traumatic injury survivors.Psychoneuroendocrinology · 2022Article
- Causal discovery replicates symptomatic and functional interrelations of posttraumatic stress across five patient populations.Frontiers in psychiatry · 2022Article
- The neurocognitive profile of post-traumatic stress disorder (PTSD), major depressive disorder (MDD), and PTSD with comorbid MDD.Brain and behavior · 2021Article
- Psychiatric comorbidity of developmental trauma disorder and posttraumatic Stress disorder: findings from the DTD field trial replication (DTDFT-R).European journal of psychotraumatology · 2021Article
- Prospective prediction of PTSD diagnosis in a nationally representative sample using machine learning.BMC psychiatry · 2020Article
- The association of depression and posttraumatic stress disorder with the metabolic syndrome in a multi-ethnic cohort: the HELIUS study.Social psychiatry and psychiatric epidemiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundAlthough PTSD-major depressive disorder (MDD) co-morbidity is well-established, the vast majority of studies have examined comorbidity at the level of PTSD total severity, rather than at the level of specific PTSD symptom clusters. This study aimed to examine the long-term associations between MDD and PTSD symptom clusters (intrusion, avoidance, hyperarousal), and the moderating role of gender in these associations.
methods942 residents of urban Detroit neighborhoods were interviewed at 3 waves, 1 year apart. At each wave, they were assessed for PTSD, depression, trauma exposure, and stressful life events.
resultsAt all waves, hyperarousal was the PTSD cluster most strongly correlated with MDD. For the full sample, a reciprocal relationship was found between MDD and all three PTSD clusters across time. Interestingly, the relative strength of associations between MDD and specific PTSD clusters changed over time. Women showed the same bidirectional MDD-PTSD pattern as in the entire sample, while men sometimes showed non-significant associations between early MDD and subsequent PTSD clusters. LIMITATIONS: First, our analyses are based on DSM-IV criteria, as this was the existing edition at the time of this study. Second, although this is a longitudinal study, inferences regarding temporal precedence of one disorder over another must be made with caution.
conclusionsEarly identification of either PTSD or MDD following trauma may be crucial in order to prevent the development of the other disorder over time. The PTSD cluster of hyper-arousal may require special therapeutic attention. Also, professionals are encouraged to develop more gender-specific interventions post-trauma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.