Trial reportEuropean journal of pediatrics2017
The course of skull deformation from birth to 5 years of age: a prospective cohort study.
Trial report in European journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Pediatric Manual Therapy in the Positional Plagiocephaly
Efficacy of Pediatric Integrative Manual Therapy in Babies With Deformational Plagiocephaly and Congenital Muscular Torticollis
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guidance strategies for infantile asymmetry prevention: a systematic review.BMC pediatrics · 2025Pooled it
- Use of orthotic helmets in children with positional plagiocephaly and brachycephaly: a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Pooled it
- Physical Therapy Management of Congenital Muscular Torticollis: A 2018 Evidence-Based Clinical Practice Guideline From the APTA Academy of Pediatric Physical Therapy.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association · 2018Guideline
- Decreased skull growth in positional plagiocephaly patients undergoing helmet therapy.Brain & spine · 2026Article
- Spinal mobilization in infants reconsidered.The Journal of manual & manipulative therapy · 2025Article
- Assessing the Evidence for Nonobstetric Risk Factors for Deformational Plagiocephaly: Systematic Review and Meta-Analysis.Interactive journal of medical research · 2024Review
- Predictive Value of Sonographic Parameters on the Effects of Cranial Molding Helmet Therapy in Infants with Positional Plagiocephaly.Diagnostics (Basel, Switzerland) · 2024Article
- Effectiveness of Conservative Treatments in Positional Plagiocephaly in Infants: A Systematic Review.Children (Basel, Switzerland) · 2023Review
- Parents' and healthcare professionals' perspectives on manual therapy in infants: A mixed-methods study.PloS one · 2023Article
- Cranial Shape in Infants Aged One Month Can Predict the Severity of Deformational Plagiocephaly at the Age of Six Months.Journal of clinical medicine · 2022Article
- Average Models and 3-dimensional Growth Patterns of the Healthy Infant Cranium.Plastic and reconstructive surgery. Global open · 2020Article
- Two-Dimensional Image-Based Screening Tool for Infants with Positional Cranial Deformities: A Machine Learning Approach.Diagnostics (Basel, Switzerland) · 2020Article
- Infant Cranial Deformity: Cranial Helmet Therapy or Physiotherapy?International journal of environmental research and public health · 2020Article
- A new parameter for the management of positional plagiocephaly: the size of the anterior fontanelle matters.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Craniofacial Asymmetry from One to Three Years of Age: A Prospective Cohort Study with 3D Imaging.Journal of clinical medicine · 2019Article
- A 3D Follow-Up Study of Cranial Asymmetry from Early Infancy to Toddler Age after Preterm versus Term Birth.Journal of clinical medicine · 2019Article
- Infant/toddler motor skills as predictors of cognition and language in children with and without positional skull deformation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- The ties that bind: Cradling in Tajikistan.PloS one · 2018Article
- Positional Skull Deformities.Deutsches Arzteblatt international · 2017Review
- Gahvora cradling in Tajikistan: Cultural practices and associations with motor development.Child developmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a continuation of a prospective longitudinal cohort study in a healthy population on the course of skull shape from birth to 24 months, at 5 years of age, 248 children participated in a follow-up assessment using plagiocephalometry (ODDI-oblique diameter difference index, CPI-cranio proportional index). Data from the original study sampled at birth, 7 weeks, 6, 12, and 24 months were used in two linear mixed models. MAIN
findings(1) if deformational plagiocephaly (ODDI <104%) and/or positional preference at 7 weeks of age are absent, normal skull shape can be predicted at 5 years of age; (2) if positional preference occurs, ODDI is the highest at 7 weeks and decreases to a stable lowest value at 2 and 5 years of age; and (3) regarding brachycephaly, all children showed the highest CPI at 6 months of age with a gradual decrease over time.
conclusionThe course of skull deformation is favourable in most of the children in The Netherlands; at 5 years of age, brachycephaly is within the normal range for all children, whereas the severity of plagiocephaly is within the normal range in 80%, within the mild range in 19%, and within the moderate/severe range in 1%. Medical consumption may be reduced by providing early tailored counselling. What is Known: • Skull deformation prevalence increased after recommendations against Sudden Infant Death Syndrome, little is known about the longitudinal course. • Paediatric physical therapy intervention between 2 and 6 months of age reduces deformational plagiocephaly at 6 and 12 months of age. What is New: • The course of skull deformation is favourable in most of the children in The Netherlands; at 5 years of age, deformational brachycephaly is within the normal range for all children, whereas the severity of deformational plagiocephaly is within the normal range in 80%, within the mild range in 19%, and within the moderate to severe range in only 1%. • Paediatric physical therapy intervention does not influence the long-term outcome; it only influences the earlier decrease of the severity of deformational plagiocephaly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.