Evidence map›Paper›PMID 27815595›Full record

ReviewCellular and molecular life sciences : CMLS2017

Ga

Danielle Kamato, Partha Mitra, Felicity Davis, Narin Osman, Rebecca Chaplin, Peter J Cabot, Rizwana Afroz, Walter Thomas, Wenhua Zheng, Harveen Kaur and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. MAPK signaling and angiopoietin-2 contribute to endothelial permeability in capillary malformations.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Syndecans modulate ghrelin receptor signaling.Journal of molecular endocrinology · 2025
    Article
  6. Article
  7. Review
  8. The role of Gαq in regulating NLRP3 inflammasome activation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  9. PGE2 Potentiates Orai1-Mediated Calcium Entry Contributing to Peripheral Sensitization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Review
  11. The Bacterial GJournal of chemical ecology · 2023
    Article
  12. De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.Protein science : a publication of the Protein Society · 2023
    Article
  13. bioRxiv : the preprint server for biology · 2023
    Article
  14. Article
  15. Selective optogenetic control of GNature communications · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Combined Inhibition of GαClinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Danielle KamatoSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Partha MitraSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Felicity DavisSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Narin OsmanSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Rebecca ChaplinSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Peter J CabotSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia.
Rizwana AfrozDepartment of Biochemistry, Primeasia University, Banani, 1213, Bangladesh.
Walter ThomasSchool of Biomedical Sciences, The University of Queensland, St. Lucia, QLD, 4102, Australia.
Wenhua ZhengFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Harveen KaurDepartment of Chemistry, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Margaret BrimbleDepartment of Chemistry, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Peter J LittleSchool of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia. p.little@uq.edu.au.
University of Queensland · AURMIT University · AUUniversity of Auckland · NZPrimeasia University · BDUniversity of Macau · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seven transmembrane G protein-coupled receptors (GPCRs) have gained much interest in recent years as it is the largest class among cell surface receptors. G proteins lie in the heart of GPCRs signalling and therefore can be therapeutically targeted to overcome complexities in GPCR responses and signalling. G proteins are classified into four families (G

Indexed as

Amino Acid SequenceAnimalsDepsipeptidesDrug DiscoveryGTP-Binding Protein alpha Subunits, Gq-G11GTP-Binding ProteinsHumansModels, MolecularPeptides, CyclicProtein ConformationProtein IsoformsSequence AlignmentSignal TransductionDepsipeptidesFR900359GTP-Binding Protein alpha Subunits, Gq-G11GTP-Binding ProteinsPeptides, CyclicProtein IsoformsYM-254890AtherosclerosisG alpha qGPCRsG Protein-coupled receptorsG proteinsHyperelongationIsoformsPAR-1

Identifiers

PMID27815595
PMCPMC11107756
OpenAlexW2548844238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.