ArticleInternational journal of public health2017
Gallstone disease and mortality: a cohort study.
Article in International journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Association between Gallstone Disease and Cardiovascular Disease: A Systematic Review and Meta-Analysis.Reviews on recent clinical trials · 2025Pooled it
- Association Between Gallstone Disease and Risk of Mortality of Cardiovascular Disease and Cancer: A Systematic Review and Meta-Analysis.Cardiovascular & hematological disorders drug targets · 2024Pooled it
- Pooled it
- Screen-detected gallstone disease and cardiovascular disease.European journal of epidemiology · 2017Trial
- Prevalence of gallstone disease in India: insights from a community-based cross-sectional study.BMJ public health · 2026Article
- Asymptomatic gallstone disease: Re-evaluating the threshold for surgical options in the era of precision medicine.World journal of gastrointestinal surgery · 2025Review
- Association between dietary fiber intake and gallstones among American adults: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- The association between life's essential 8 and gallstones: A cross-sectional study.Scientific reports · 2025Article
- [Food consumption patterns and risk of gallstone disease (GD): Case and Control Study in Rosario Argentina.]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024Article
- [Establishment and Validation of a Predictive Model for Gallstone Disease in the General Population: A Multicenter Study].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Liver Function-Related Indicators and Risk of Gallstone Diseases-A Multicenter Study and a Systematic Review and Meta-Analysis.Gastroenterology research and practice · 2024Article
- Longitudinal Study of Comorbidities and Clinical Outcomes in Persons with Gallstone Disease Using Electronic Health Records.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- An epidemiological investigation of gallstone disease among patients admitted to Shahid Rahimi teaching hospital in Khorramabad in 2016-2020.African health sciences · 2023Article
- Cholecystectomy for asymptomatic gallstones: Markov decision tree analysis.World journal of clinical cases · 2022Review
- Synchronous biliary gallstones and colorectal cancer: A single center analysis.Experimental and therapeutic medicine · 2022Article
- Important risk factors for gallstones after laparoscopic gastrectomy: a retrospective study.BMC surgery · 2022Article
- The increasing incidence and high body mass index-related burden of gallbladder and biliary diseases-A results from global burden of disease study 2019.Frontiers in medicine · 2022Article
- Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study.BMJ open · 2020Article
- Management of complicated gallstones in the elderly: comparing surgical and non-surgical treatment options.Gastroenterology report · 2019Article
- Gastrointestinal defects in gallstone and cholecystectomized patients.European journal of clinical investigation · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this cohort study was to determine whether subjects with gallstone disease identified by screening of a general population had increased overall mortality when compared to gallstone-free participants and to explore causes of death.
methodsThe study population (N = 5928) was examined 1982-1992 and included an abdominal ultrasound examination to assess gallstone status, a physical examination, blood samples, and a questionnaire about medical history. Participants were followed up through national registers until 2015. Multiple adjusted Cox regression models were built.
resultsGallstone disease was present in 10%. Mortality was 46% during median 24.7 years of follow-up with 1% lost. Overall mortality and death from cardiovascular diseases were significantly associated to gallstone disease. Death from unknown causes was significantly associated to gallstone disease and death from cancer and gastrointestinal disease was not associated. No differences in mortality for ultrasound-proven gallstones or cholecystectomy were identified.
conclusionsGallstone disease is associated with increased overall mortality and to death from cardiovascular disease. Gallstones may be considered a possible cardiometabolic risk factor. Other unknown factors also seem to play a role.
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Registered trials
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